Advertisements

We're a little crazy, about science!

Posts tagged “amyloid-β

Beta secretase inhibitors offer treatment for Alzheimer’s disease

alzhemers

With each new amyloid-targeting treatment for Alzheimer’s disease that has been developed, there has been a corresponding concern. For example, antibodies targeting amyloid-β peptide (Aβ) produce inflammation in the brain in some patients. Gamma secretase inhibitors tend to produce adverse effects by interacting with Notch, an important pathway for cellular signaling. However, a new target for alzheimer’s is offering some new hope.

(more…)

Advertisements