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Posts tagged “CRISPR

Stem cell gene therapy could be key to treating Duchenne muscular dystrophy

crispr cas9 art

crispr cas9 art

Scientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and Center for Duchenne Muscular Dystrophy at UCLA have developed a new approach that could eventually be used to treat Duchenne muscular dystrophy. The stem cell gene therapy could be applicable for 60 percent of people with Duchenne, which affects approximately 1 in 5,000 boys in the U.S. and is the most common fatal childhood genetic disease.


Scientists discover new system for human genome editing

Bacteriophages attacking bacteria, TEM

CRISPR systems help bacteria defend against viral attack (shown here).
These systems have been adapted for use as genome editing tools in
human cells.
Image credit goes to: Ami Images/Science Photo Library.

A team including the scientist who first harnessed the revolutionary CRISPR-Cas9 system for mammalian genome editing has now identified a different CRISPR system with the potential for even simpler and more precise genome engineering. In the study researchers describe the unexpected biological features of this new system and demonstrate that it can be engineered to edit the genomes of human cells.


Scientists create worlds first genetically modified human embryos


A funny thing happened on the way to the publisher. In a world first, China has successfully created genetically modified human embryos. It was certainly an amazing piece of science, but the paper was rejected by both Nature and Science. Not because the study was flawed, or because the data was falsified, the paper was rejected for ethical reasons.


Gene Editing in Live Mice Cures Rare Liver Disease


A chromosome [the “x”] with a DNA strand ‘close up’ in the circle.

Scientists at MIT have successfully used the CRISPR method to replace faulty genes in live mice, curing a rare liver disease. This type of genetic modification has been done in the past, but only in vitro [think petri dish]. Making this a monumental step forward for curing people who are suffering from genetic disease.