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Posts tagged “Genetics

Day 54: The Science Behind Real Zombies

Zombies: Science Fiction vs. Fact

zombies ahead

Time for a break from stochastic processes, at least for the moment. Every year here we update and post our favorite Halloween tradition!  So today we bring you the science fact and fiction behind the undead. Zombies, those brain loving little things are everywhere. Sure, we are all familiar with the classic  zombie, but did you know that we aren’t the only zombie lovers out there? It turns out that nature has its own special types of zombies, but this isn’t a science fiction movie, this is science fact! Sometimes fact can be scarier than fiction, so let’s dive in. Let’s talk zombies.

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The science behind real life zombies

Zombies: Science Fiction vs. Fact

zombies ahead

In the spirit of Halloween we bring you the science fact and fiction behind the undead. Zombies, those brain loving little guys, (and girls) are everywhere. Sure, we are all familiar with the classic  zombie, but did you know that we aren’t the only zombie lovers out there? It turns out that nature has its own special types of zombies, but this isn’t a science fiction movie, this is science fact! Sometimes fact can be scarier than fiction, so let’s dive in.

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High cholesterol triggers mitochondrial oxidative stress leading to osteoarthritis

knee problems

knee problems

High cholesterol might harm more than our cardiovascular systems. New research using animal models suggests that high cholesterol levels trigger mitochondrial oxidative stress on cartilage cells, causing them to die, and ultimately leading to the development of osteoarthritis.

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Vitamins A and C help erase cell memory

epigenetics

epigenetics

Vitamins A and C aren’t just good for your health, they affect your DNA too. Researchers have discovered how vitamins A and C act to modify the epigenetic ‘memory’ held by cells; insight which is significant for regenerative medicine and our ability to reprogramme cells from one identity to another.

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Mental illness genetically linked to drug use and misuse

anxiety depression

anxiety depression

There are many reports of drug use leading to mental health problems, and we all know of someone having a few too many drinks to cope with a bad day. Many people who are diagnosed with a mental health disorder indulge in drugs, and vice versa. As severity of both increase, problems arise and they become more difficult to treat. But why substance involvement and psychiatric disorders often co-occur is not well understood.

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Largest-ever study reveals environmental impact of genetically modified crops

gmo crops

gmo crops

According to new research, widespread adoption of genetically modified crops has decreased the use of insecticides, but increased the use of weed-killing herbicides as weeds become more resistant. This is the largest study of genetically modified crops and pesticide use to date. The team of economists studied annual data from more than 5,000 soybean and 5,000 maize farmers in the U.S. from 1998 to 2011, far exceeding previous studies that have been limited to one or two years of data.

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A microRNA plays role in major depression

mental health

mental health

A tiny RNA appears to play a role in producing major depression, the mental disorder that affects as many as 250 million people a year worldwide. Major depression, formally known as major depressive disorder, or MDD, brings increased risk of suicide and is reported to cause the second-most years of disability after low-back pain.

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Antimicrobial chemicals found with antibiotic-resistance genes in indoor dust

pokemon evolution

pokemon evolution

Researchers have found links between the levels of antimicrobial chemicals and antibiotic-resistance genes in the dust of an aging building used for athletics and academics. One of the antimicrobials seen in the study is triclosan, a commonly used antibacterial ingredient in many personal care products.

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The Genesis Project: New life on exoplanets

exoplanets

exoplanets

Can life be brought to celestial bodies outside our solar system, which are not permanently inhabitable? A new essay that has been published is trying to deal with this question. Over the last several years, the search for exoplanets has shown that very different types exist leading to new questions and a variety of possible answers.

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Trauma’s epigenetic fingerprint observed in children of Holocaust survivors

I swear I didn't kill anyone
I swear I didn't kill anyone

Image credit goes to the one and only — very talented — Lora Zombie

The children of traumatized people have long been known to be at increased risk for posttraumatic stress disorder (PTSD), and mood and anxiety disorders. However, there are very few opportunities to examine biologic alterations in the context of a watershed trauma in exposed people and their adult children born after the event.

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Is depression in parents, grandparents linked to grandchildren’s depression?

depression

depression

If you read my blog often, it’s no surprise I suffer from PTSD, depression, and anxiety issues. Maybe it’s from my military service, but maybe it’s my father’s, or his father’s, maybe it’s an insidious family legacy that was just never noticed. This is because having both parents and grandparents with major depressive disorder (MDD) was associated with higher risk of MDD for grandchildren, which could help identify those who may benefit from early intervention.

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Microcephaly discoveries in non-Zika cases explain abnormal brain growth

microcephaly

microcephaly

Long before Zika virus made it a household word, the birth defect called microcephaly puzzled scientists and doctors — even as it changed the lives of the babies born with it during the pre-Zika era. But new discoveries reported by an international team of scientists may help explain what happens in the developing brains of babies still in the womb, causing them to be born with small brains and heads.

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From Sci Fi to reality: Unlocking the secret to growing new limbs

growing new limbs

growing new limbs

Many lower organisms retain the miraculous ability to regenerate form and function of almost any tissue after injury. Humans share many of our genes with these organisms, but our capacity for regeneration is limited. So scientists are studying the genetics of these organisms to find out how regenerative mechanisms might be activated in humans.

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FAMIN or feast? Newly discovered mechanism influences how immune cells ‘eat’ invaders

macrophage

macrophage

A new mechanism that affects how our immune cells perform – and hence their ability to prevent disease – has been discovered by an international team of researchers. To date, researchers have identified hundreds of genetic variants that increase or decrease the risk of developing diseases from cancer and diabetes to tuberculosis and mental health disorders.

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Alzheimer’s genetics point to new research direction

Genetics of alzheimer's

Genetics of alzheimer's

A analysis of genetic mutations which cause early-onset Alzheimer’s disease suggests a new focus for research into the causes of the disease. Previous research has revolved around the idea that accumulation in the brain of a small, sticky protein fragment — amyloid beta — causes Alzheimer’s disease.

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Fear factor: A new genetic candidate for treating PTSD

I swear I didn't kill anyone
I swear I didn't kill anyone

Image credit goes to the very talented: Lora Zombie

Researchers have identified a new genetic candidate for testing therapies that might affect fear learning in people with PTSD or other conditions. Individuals with trauma- and stress-related disorders can manifest symptoms of these conditions in a variety of ways. Genetic risk factors for these and other psychiatric disorders have been established but do not explain the diversity of symptoms seen in the clinic – why are some individuals affected more severely than others and why do some respond better than others to the same treatment?

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New tool brings personalized medicine closer

personalized medicine

personalized medicine

Scientists have developed a powerful tool for exploring and determining the inherent biological differences between individuals, which overcomes a major hurdle for personalized medicine.

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The truth is out there: Scientists unlock X-Files DNA mystery

x files

x files

Scientists have unlocked a crucial part of the mystery as to how our DNA can replicate and repair itself – something which is essential for all life forms. The new research has revealed how branched DNA molecules are removed from the iconic double-helical structure -a process which scientists have been looking to unlock for over 20 years.

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New muscular dystrophy drug target identified

DMD

DMD

Scientists have discovered that muscle cells affected by muscular dystrophy contain high levels of an enzyme that impairs muscle repair. This finding provides a new target for potential drug treatments for the disease, which currently has no cure. Muscular dystrophy (MD) is an inherited genetic condition that gradually causes a weakening of muscles.

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Converting cells to burn fat, not store it

carb loading cat

carb loading cat

Researchers have uncovered a new molecular pathway for stimulating the body to burn fat — a discovery that could help fight obesity and cardiovascular disease.By focusing on a protein known as folliculin, and knocking out the gene that produces it in fat cells, the researchers triggered a series of biomolecular signals that switched the cells from storing fat to burning it.

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Bacteria are individualists

cultured bacteria

cultured bacteria

No two bacteria are identical – even when they are genetically the same. A new study from researchers reveals the conditions under which bacteria become individualists and how they help their group grow when times get tough. Whether you are a human or a bacterium, your environment determines how you can develop.

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Sleep loss detrimental to blood vessels

Sleep deprived

Sleep deprived

We all know lack of sleep is bad for the brain, but lack of sleep has even been found to impact the activation of the immune system, inflammation, carbohydrate metabolism and the hormones that regulate appetite. Worse still, researchers in a new study have found that sleep loss also influences cholesterol metabolism.

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Bad news, fructose alters hundreds of brain genes

high sugar milkshake

high sugar milkshake

Got a sweet tooth? Maybe you even have some sugary goodness with you right now… as you are reading this. Well you may want to put that down.We know a range of diseases — from diabetes to cardiovascular disease, and from Alzheimer’s disease to attention deficit hyperactivity disorder — are linked to changes to genes in the brain. Unfortunately for those who love their pop tarts, a new study  has found that hundreds of those genes can be damaged by fructose, a sugar that’s common in the Western diet, in a way that could lead to those diseases.

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Bigger brains led to bigger bodies in our ancestors

brain sizes

brain sizes

New research suggests that humans became the large-brained, large-bodied animals we are today because of natural selection to increase brain size. The work contradicts previous models that treat brain size and body size as independent traits responding to separate evolutionary pressures. Instead, the study shows that brain size and body size are genetically linked and that selection to increase brain size will “pull along” body size.

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