Last summer I had some sort of autoimmune thing kick up. Frankly I’m not sure it was autoimmune or what the hell it was, but it hurt, left me feeling exhausted, and caused my hands, face, and elbows to form raised red spots that later peeled off (here). It was incredibly painful, made me question the minor breakouts of whatever it was that had been going on for a good ten years or so prior, and was a red flag that I was not okay. But the pandemic has been ongoing so getting attention from the VA, which is notoriously awful, had been difficult. Had been, I finally got the chance to see someone.(more…)
Awhile back I wrote a post on everything you needed to know about the COVID vaccine (here), I talked about the science, my experience with it (as someone who got vaccinated very early on), and more importantly why you should feel safe getting your shots too. Very ominously I mentioned that the target for the vaccine was the spike protein because it would (ideally, but not for sure) be conserved across mutations, well it’s time for an update and the news isn’t great.(more…)
Well today is day 1 post COVID vaccine. That was the first of two shots that I need to get, the second one will be in the middle of January (already scheduled). Since I was lucky enough to get the vaccine I thought I would talk a bit about the side effects of it, at least from my end. My hope is to help people relax a bit and when it becomes available to the public, you won’t be nervous to get it done.(more…)
Today is the day! About a week ago I got an email letting me know that I could be vaccinated. While I’m a researcher in a hospital, my work involves a high risk population (people with spinal cord injury) so I’m front facing with patients on a regular basis. I’m also disabled which may have factored into my group placement. Whatever the case, I got a spot in line and now it’s my turn. My Co-PI who’s lab I work out of already got his, but he was in a higher group than I was. As usual I have some thoughts on all this…(more…)
Don’t do it. Seriously, why are we having this discussion right now? It makes no sense, there is a pandemic going on and if you live specifically in the US (which I do) you’re going to need to stay home. Sure the holidays can be an important time of year for families, but do we really need a holiday to celebrate with our family? Why not wait until this is over? More importantly is it worth putting all of them, yourself, and the people you come in contact with at risk?(more…)
Neu5Gc, a non-human sialic acid sugar molecule common in red meat that increases the risk of tumor formation in humans, is also prevalent in pig organs, with concentrations increasing as the organs are cooked, a study has found. The research suggests that Neu5Gc may pose a significant health hazard among those who regularly consume organ meats from pigs.
Pathogen epitopes are fragments of bacterial or viral proteins. Attached to the surface structure of cells, they prompt the body’s immune system to mount a response against foreign substances. Researchers have determined that nearly a third of all existing human epitopes consist of two different fragments. Known as ‘spliced epitopes’, these types of epitopes have long been regarded as rare. The fact that they are so highly prevalent might, among other things, explain why the immune system is so highly flexible.
Bladder cancer is the seventh most common cancer in males worldwide. Every year, about 20,000 people in Japan are diagnosed with bladder cancer, of whom around 8,000–mostly men–succumb to the disease. Bladder cancers can be grouped into two types: non-muscle-invasive cancers, which have a five-year survival rate of 90 percent, and muscle-invasive cancers, which have poor prognoses.
High cholesterol might harm more than our cardiovascular systems. New research using animal models suggests that high cholesterol levels trigger mitochondrial oxidative stress on cartilage cells, causing them to die, and ultimately leading to the development of osteoarthritis.
Increasingly powerful computers using ever-more sophisticated programs are challenging human supremacy in areas as diverse as playing chess and making emotionally compelling music. But can digital diagnosticians match, or even outperform, human physicians? The answer, according to a new study, is “not quite.”
A team of researchers has found that consuming an omega-3 fatty acid called DHA, or docosahexaenoic acid, can stop a known trigger of lupus and potentially other autoimmune disorders. DHA can be found in fatty, cold-water fish and is produced by the algae that fish eat and store in their bodies. It can be found in fish oil supplements as well, used by more than 30 million Americans.
Children with HIV who can resist the disease progressing could point the way to new treatments for HIV infection that are more widely applicable to infected adults and children alike, an international team of researchers has found.
Using archival documents, a new report examines the sugar industry’s role in coronary heart disease research and suggests the industry sponsored research to influence the scientific debate to cast doubt on the hazards of sugar and to promote dietary fat as the culprit in heart disease.
It’s advice most smokers with children probably take lightly, but they shouldn’t. Parents and policy advocates should take a “zero tolerance” approach to exposing children to secondhand cigarette smoke, which can be responsible for lifelong cardiovascular consequences in addition to respiratory and other health issues.
Household dust exposes people to a wide range of toxic chemicals from everyday products, according to a new study. A multi-institutional team conducted a first-of-a-kind meta-analysis, compiling data from dust samples collected throughout the United States to identify the top ten toxic chemicals commonly found in dust.
Scientists trying to find ways to regenerate a damaged heart have shed more light on the molecular mechanisms that could one day make this a reality. Whilst other organs such as the liver can regenerate, the heart muscle has very little ability to do so after suffering damage, such as a heart attack.
In the womb the body is able to produce heart muscle cells but soon after birth it effectively stops producing them.
New research has shown that the corticosteroid deflazacort is a safe and effective treatment for Duchenne muscular dystrophy. The findings could pave the way for first U.S.-approved treatment for the disease.
Why do some people want to live a very long time, while others would prefer to die relatively young? In a latest study, a team of researchers investigated how long young and middle-aged adults in the United States say they want to live in relation to a number of personal characteristics. The results showed that more than one out of six people would prefer to die younger than age 80, before reaching average life expectancy.
A stroke can happen at any age, and as with anything that involves the brain, a few seconds can be life altering. Usually the rule is time lost is brain lost, but there might be some good news regarding that, researchers found that omega-3 fatty acids reduced brain damage in a neonatal mouse model of stroke.
Results of a new study by environmental health scientists suggest that inexpensive cloth masks worn by people who hope to reduce their exposure to air pollution vary widely in effectiveness and could be giving users a false sense of security, especially in highly polluted areas.
There’s a reason it’s called a gut feeling. The brain and the gut are connected by intricate neural networks that signal hunger and satiety, love and fear, even safety and danger. These networks employ myriad chemical signals that include dopamine, a powerful neurotransmitter most famous for its role in reward and addiction.
Long before Zika virus made it a household word, the birth defect called microcephaly puzzled scientists and doctors — even as it changed the lives of the babies born with it during the pre-Zika era. But new discoveries reported by an international team of scientists may help explain what happens in the developing brains of babies still in the womb, causing them to be born with small brains and heads.
Many lower organisms retain the miraculous ability to regenerate form and function of almost any tissue after injury. Humans share many of our genes with these organisms, but our capacity for regeneration is limited. So scientists are studying the genetics of these organisms to find out how regenerative mechanisms might be activated in humans.
The high levels of caffeine in energy drinks may lead to cardiac complications. A new case report adds to previous reports of adverse cardiovascular events related to consuming energy drinks, including abnormal heart rhythms (arrhythmias).
A new mechanism that affects how our immune cells perform – and hence their ability to prevent disease – has been discovered by an international team of researchers. To date, researchers have identified hundreds of genetic variants that increase or decrease the risk of developing diseases from cancer and diabetes to tuberculosis and mental health disorders.
One of the main mysteries confounding development of an HIV vaccine is why some people infected with the virus make the desired antibodies after several years, but a vaccine can’t seem to induce the same response.
Medication roulette, if you have ever had to deal with depression or other types of mental illness you know what I’m talking about. You take a pill that could help or could cause all sorts of horrid side effects. You cross your fingers as you take that first pill and in the 4-6 weeks it takes to start working you cross your fingers, hope, wish and probably even dread the outcome. But why does it take so long for antidepressants to start working in the first place and what could be done to change that?
Biologists have found that a protein that plays a key role in the lives of stem cells can bolster the growth of damaged muscle tissue, a step that could potentially contribute to treatments for muscle degeneration caused by old age and diseases such as muscular dystrophy. The results show that a particular type of protein called integrin is present on the stem cell surface and used by stem cells to interact with, or “sense” their surroundings.
Researchers have found evidence that bone marrow transplantation may one day be beneficial to a subset of patients suffering from amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder more commonly known as Lou Gehrig’s disease.
Eating a type of powdered food supplement, based on a molecule produced by bacteria in the gut, reduces cravings for high-calorie foods such as chocolate, cake and pizza, a new study suggests. Scientists asked 20 volunteers to consume a milkshake that either contained an ingredient called inulin-propionate ester, or a type of fibre called inulin.
The antibiotic arms race is on, while we are rushing to find new antibiotics, bacteria are working on finding ways around them. With that in mind, a new experimental antibiotic developed by a team of scientists successfully treats the deadly MRSA infection and restores the efficacy of a commonly prescribed antibiotic that has become ineffective against MRSA.
New research is giving a whole new meaning to feeling your skin crawl. Skin cells typically spend their entire existence in one place on your body. But researchers have seen how the cells will alter the proteins holding them in place and move to repair a wound.
Scientists have discovered that muscle cells affected by muscular dystrophy contain high levels of an enzyme that impairs muscle repair. This finding provides a new target for potential drug treatments for the disease, which currently has no cure. Muscular dystrophy (MD) is an inherited genetic condition that gradually causes a weakening of muscles.
Countries that implement government-mandated vaccinations for chickenpox see a sharp drop in the number of Google searches for the common childhood disease afterward, demonstrating that immunization significantly reduces seasonal outbreaks. That’s one of the findings from a new study that analyzed thousands of Google searches for “chickenpox.”
A team of scientists have shown that the brains of patients with schizophrenia have the capacity to reorganize and fight the illness. This is the first time that imaging data has been used to show that our brains may have the ability to reverse the effects of schizophrenia.
Scientists have identified the trigger for immune cells’ inflammatory response — a discovery that may pave the way for new treatments for many human diseases. Immune cells play essential roles in the maintenance and repair of our bodies. When we injure ourselves, immune cells mount a rapid inflammatory response to protect us against infection and help heal the damaged tissue.
The development of antiretroviral therapy, a combination of drugs that slows the replication of HIV in the body, has transformed the treatment of this infection. What was once a certain death sentence is now a chronic condition that people can live with for decades. But this therapy has drawbacks. There are side effects, including kidney problems, decreased bone density, and gastrointestinal problems. And if a person discontinues his or her treatment, even missing a few doses, the level of the virus in the body is able to rebound quickly.
A pioneering study of worldwide sleep patterns combines math modeling, mobile apps and big data to parse the roles society and biology each play in setting sleep schedules. The study used a free smartphone app that reduces jetlag to gather robust sleep data from thousands of people in 100 nations. The researchers examined how age, gender, amount of light and home country affect the amount of shut-eye people around the globe get, when they go to bed, and when they wake up.
Insomnia, fun fact those of us who have served or are serving in the military have a much higher incidence of sleep problems. So if you are like me and have ever been prescribed something to help you sleep, you know that there are some unwanted side effects. For instance the time I lost memory of a whole day of interacting with people to the ambien I had taken the night before, not fun. Thankfully Danish researchers found that the level of salts in the brain plays a critical role in whether we are asleep or awake.
No one knows Traumatic brain injuries (TBI) quite like veterans. Unfortunately, it is a major cause of mortality and morbidity, often causing lifelong disability for those who survive. There is simply no treatment, jut care, but a new study might change that. Stem cell therapy has recently been receiving attention as a way to promote recovery for injuries to the central nervous system (CNS) which opens the door for treatment of a TBI.
Well, we know now that ZIKA causes microcephaly, at least that is the latest findings. Things don’t look so good on other ZIKA fronts either, a new study confirms that the virus can be transmitted sexually. The analyses have shown 100% genetic correlation between the form of the virus present in a man who contracted the virus in Brazil and that of a woman who had never travelled in the epidemic area, but who had sexual relations with him.
If Parkinson’s disease wasn’t bad enough for families to have to learn to deal with, about 80% of patients also develop dementia. That’s the problem with the brain; while it has the amazing ability to adapt to just about anything, it can’t fix everything. There are no particularly good solutions to Parkinson’s or dementia, however, early detection of dementia is key to keeping it at bay and a new study may have a way to do just that.
If you see me on the street and I am running, there is a good chance you should be running as well, because something dangerous is coming. I don’t run, I hate to run, I loathe running, did I mention I don’t like to run? Maybe it’s all the running I did in the military, or if a new study is correct, it may have to do with my mother. Which is good, because now I can blame someone else for my hatred of running.
If you’re a transplant recipient you know that transplant organs are a veritable ticking time bomb waiting to be rejected by your well-meaning (but stupid) body. Not only can you do everything right and still have the organs rejected, you have to take a steady stream of expensive pills to inhibit the immune system and stop the body from launching its attack. Don’t throw your pill organizers away just yet, but soon.