Sugar addiction: Discovery of a brain sugar switch
Researchers have discovered that our brain actively takes sugar from the blood. Prior to this, researchers around the world had assumed that this was a purely passive process. An international team reports that transportation of sugar into the brain is regulated by so-called glial cells that react to hormones such as insulin or leptin; previously it was thought that this was only possible for neurons.
What happens in the Lab doesn't have to stay in the Lab!
Brain activity and response to food cues differ in severely obese women
The brain’s reward centers in severely obese women continue to respond to food cues even after they’ve eaten and are no longer hungry, in contrast to their lean counterparts. The study compared attitudes and the brain activity of 15 severely obese women (those with a body mass index greater than 35) and 15 lean women (those with a BMI under 25).
What happens in the Lab doesn't have to stay in the Lab!
New supplement may switch off cravings for high-calorie foods
Eating a type of powdered food supplement, based on a molecule produced by bacteria in the gut, reduces cravings for high-calorie foods such as chocolate, cake and pizza, a new study suggests. Scientists asked 20 volunteers to consume a milkshake that either contained an ingredient called inulin-propionate ester, or a type of fibre called inulin.
What happens in the Lab doesn't have to stay in the Lab!
Brain cells that aid appetite control identified
It’s rare for scientists to get what they describe as “clean” results without spending a lot of time repeating the same experiment over and over again. But when researchers saw the mice they were working with doubling their weight within a month or two, they knew they were on to something.
What happens in the Lab doesn't have to stay in the Lab!
Can exercise be replaced with a pill?
Everyone knows that exercise improves health, and ongoing research continues to uncover increasingly detailed information on its benefits for metabolism, circulation, and improved functioning of organs such as the heart, brain, and liver. With this knowledge in hand, scientists may be better equipped to develop “exercise pills” that could mimic at least some of the beneficial effects of physical exercise on the body. But a review of current development efforts ponders whether such pills will achieve their potential therapeutic impact, at least in the near future.
What happens in the Lab doesn't have to stay in the Lab!
Diet beverage drinkers compensate by eating unhealthy food
Alcoholic drinks and sugar-sweetened beverages are associated with higher overall daily intakes, although people who drink diet beverages consume a greater percentage of non-nutritious food.
Image credit goes to: Julie McMahon
Want fries with that diet soda? You aren’t alone, and you may not be “saving” as many calories as you think by consuming diet drinks. A new study that examined the dietary habits of more than 22,000 U.S. adults found that diet-beverage consumers may compensate for the absence of calories in their drinks by noshing on extra food that is loaded with sugar, sodium, fat and cholesterol.
What happens in the Lab doesn't have to stay in the Lab!
Fish oil-diet benefits may be mediated by gut microbes
Diets rich in fish oil versus diets rich in lard produce very different bacteria in the guts of mice, reports a study from Sahlgrenska Academy published in Cell Metabolism. The researchers transferred these microbes into other mice to see how they affected health. The results suggest that gut bacteria share some of the responsibility for the beneficial effects of fish oil and the harmful effects of lard. Image credit goes to: University of Gothenburg
Diets rich in fish oil versus diets rich in lard produce very different bacteria in the guts of mice, reports a new study. The researchers transferred these microbes into other mice to see how they affected health. The results suggest that gut bacteria share some of the responsibility for the beneficial effects of fish oil and the harmful effects of lard.
What happens in the Lab doesn't have to stay in the Lab!
Body fat can send signals to brain, affecting stress response
The brain’s effect on other parts of the body has been well established. Now, a group of researchers has found that it’s a two-way street: Body fat can send a signal that affects the way the brain deals with stress and metabolism. While the exact nature of those signals remains a mystery, researchers say simply knowing such a pathway exists and learning more about it could help break a vicious cycle: Stress causes a desire to eat more, which can lead to obesity. And too much extra fat can impair the body’s ability to send a signal to the brain to shut off the stress response.
What happens in the Lab doesn't have to stay in the Lab!
That daily soda or sugary drink habit may be punishing your liver
If you enjoy a daily soda, or other tasty sugar filled drink, you may want to put it down. New research shows that a daily sugar-sweetened beverage habit may increase the risk for non-alcoholic fatty liver disease (NAFLD). The study comes from researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University and is bad news for anyone who loves sugary drinks.
What happens in the Lab doesn't have to stay in the Lab!
Psychologists share the three secrets to healthier eating
You don’t need a crazy diet to lose weight. In fact, your typical fad diet won’t help you keep weight off long term and could be harming your health. If you want to know the secrets of healthier eating, think of the kitchen fruit bowl. A fruit bowl makes fruit more convenient, attractive, and normal to eat than if the same fruit were in the bottom of the refrigerator.
What happens in the Lab doesn't have to stay in the Lab!
Special microbes make anti-obesity molecule in the gut
You’ve probably heard of all sorts of diets, paleo, low-fat, low-carb, atkins, but now microbes may just be the next diet craze. Researchers have programmed bacteria to generate a molecule that, through normal metabolism, becomes a hunger-suppressing lipid (fat). Mice that drank water laced with the programmed bacteria ate less, had lower body fat and staved off diabetes — even when fed a high-fat diet — offering a potential weight-loss strategy for humans.
What happens in the Lab doesn't have to stay in the Lab!
Is diet soda making you fat?
The diet soda controversy is still raging on, study after study has been coming in saying that it helps weight loss, it hurts weight loss, and frankly it can all be a little confusing. Well this probably won’t help matters any, a new study shows that increasing diet soda intake is directly linked to greater abdominal obesity in adults 65 years of age and older. These findings raise concerns about the safety of chronic diet soda consumption, which may increase belly fat and contribute to greater risk of metabolic syndrome and cardiovascular diseases.
What happens in the Lab doesn't have to stay in the Lab!
Science shows intermittent fasting diet could extend life
Think of it as interval training for the dinner table. Proponents of fasting style diets will be first to tell you there are health benefits, heck we’ve even covered some of the science here at the labs. Well new research shows that putting people on a intermittent fasting (or IF) diet may mimic some of the benefits of actual fasting, and that (ironically enough given their popularity) adding antioxidant supplements counteracts those benefits.
What happens in the Lab doesn't have to stay in the Lab!
Overriding muscles’ energy efficiency to burn more fat
What started as an evolutionary protection against starvation has become a biological “bad joke” for people who need to lose weight. The human body doesn’t distinguish between dieting and possible starvation, so when there is a decrease in calories consumed, human metabolism increases its energy efficiency and weight loss is resisted.
What happens in the Lab doesn't have to stay in the Lab!
Why low-carb or fasting diets are good for your health
While most research regarding fat loss focuses on the risks of being overweight, a new study shows that fasting, low-carb diets, or high-intensity exercise have specific health benefits. Specifically, researchers have found that a compound produced by the body when dieting or fasting can block a part of the immune system involved in several inflammatory disorders such as type 2 diabetes, atherosclerosis, and Alzheimer’s disease.
What happens in the Lab doesn't have to stay in the Lab!
Creating a better diet pill: The new drug that is making big promises
Losing the weight, some of us never seem to be able to do it. Whether it is poor choice in diet, a medical condition, or just a sedentary lifestyle, people everywhere are finding they can’t shed the pounds. Now there is a new drug that promises help in the weight loss department and works like nothing we’ve seen used for weight loss yet. The compound effectively stopped weight gain, lowered cholesterol, controlled blood sugar and minimized inflammation in mice, making it an excellent candidate for a rapid transition into human clinical trials.
What happens in the Lab doesn't have to stay in the Lab!
A surprising discovery about fast food portion sizes
Since the noticeable expansion of most of the worlds waistlines, people have come to lay the blame (amongst other things) almost squarely on fast food and ever increasing portion sizes. While the world and it’s leaders are dealing with this mysterious problem by trying to help push fast food chains in the direction of change, it might be surprising to know that according to new research, fast food portion sizes have changed little since 1996.
What happens in the Lab doesn't have to stay in the Lab!
Why “fat shaming” makes things worse
Thanks to the internet age we have lost touch with the fact that there is a human out there reading these words. Because of this, the golden rule –treat others the way you want to be treated — went out the window. Making fun of “fat” people now seems to be a internet hobby and that insensitivity can (and does) bleed over into “normal” non-internet life. Now a new study shows that women whose loved ones are critical of their weight tend to put on even more pounds, which is probably no surprise to people who have experienced this behavior.
What happens in the Lab doesn't have to stay in the Lab!
Scientists find a drug (currently used) to turn white fat to brown
It seems like we’ve been on a weight loss campaign here at the labs, but there just has been so much new and interesting research on the subject to report on; this is no exception. Researchers have uncovered the mechanism by which white fat cells from humans (an important distinction) gets reprogrammed to become browner.
What happens in the Lab doesn't have to stay in the Lab!
Scientists find a hormone that makes you fatter
Our waistlines are expanding, it’s no secret that around the world despite rampant hunger people are also getting fatter. While there are many things that are contributing to this — our increased food security, the cost of food, fast food, the increasing sugar supplied in food, etc — there are other theories as to why we are getting so heavy. Scientists have pointed towards bacteria, gut microbiota, and many other causes for our increased weight, now add to that list a common hormone that we all produce.
What happens in the Lab doesn't have to stay in the Lab!
Is your Stomach… Controlling your Mind?
Close the blinds, lock the doors, and find a safe place to hide. Are you alone? No, no you aren’t and you may not even be in control of your own actions. Shhh, take a deep breath. I don’t want to alarm you, but you are being controlled. No, I’m not being paranoid and while it may sound like science fiction it looks like that bacteria within us — which for the record outnumber our own cells about 100-fold — may very well be affecting both our cravings and moods to get us to eat what they want, and often are driving us toward obesity.
What happens in the Lab doesn't have to stay in the Lab!
Weight loss Stalled? Kick those Hunger Cravings!
Trying to drop the weight, but find yourself picking up more of it? Is your diet failing because you are so hungry you could eat a horse? Well a new study offers some, maybe obvious, but nevertheless helpful insights to help you wrangle in that waist line. A healthy diet will help you drop the weight, but if you aren’t sure what a healthy diet contains that might be a problem. If you are trying to cut the weight, but can’t fight the hunger you might just need to try beans!
What happens in the Lab doesn't have to stay in the Lab!
Is Fat Making you… Fat?
Fast food, let’s face it, it’s not the best for you. Yet Mcdonalds and Pizza hut are known practically world wide [although menu options differ]. With the rise of our waist lines and the shrinking cost of fast food, you might suspect a connection. Fortunately for your big mac addiction [no judgement] it isn’t what you might think. If you’re finding it harder and harder to see your toes, you might just have your brain, and not your stomach, to thank for it.
What happens in the Lab doesn't have to stay in the Lab!
Fighting the Obesity Epidemic with X-box [No, not that one]
Despite all the efforts, people are losing the war on obesity. There is probably a number of factors involved, genetics, underlying medical problems, most of all diet, but in any case we are living in a world that is slightly heavier than our historical counterparts. Maybe that’s why so many researchers are trying to find an easy way for people to better regulate their weight. Thankfully that goal is one step closer because researchers have found a protein that controls when genes are switched on or off, one that plays a key role in specific areas of the brain to regulate metabolism.
What happens in the Lab doesn't have to stay in the Lab!
To Lose the Weight, Feel the… freezer burn?
Are you so fat you can’t see your toes? Have you forgotten what toes even look like? Have you been mistaken for the infamous “Kool-aid man”? Want to shed the pounds easier than taking off your shirt? Well too bad, that is science fiction and the stuff of horrid marketing ploys and this my friends is a science website. Losing weight is hard, I’ve written several articles on it in fact. Nothing is going to be more effective at weight loss than a sensible diet, a calorie deficit and maybe some insoluble fiber that I mentioned in the very first article I’ve written.
A new companion study to this post, which I wrote not long ago not only confirms that original studies findings, but also gives insight into another factor for the mounting obesity epidemic.
What happens in the Lab doesn't have to stay in the Lab!
New Obesity drugs: Coming Soon to a Store Near You!
Afraid to go into public because you think those double doors might be a little narrow for you? Are you pretty sure you have feet, even though you haven’t seen them for awhile now? Did you recently find something you think may have been a twinkie at one point in your folds? If you answered yes to any of these questions, then science might be able to help.
Believe it or not weight gain is complex –or at least the biological aspect of it– for example hormones control our appetite and even the uptake of food. In recent years, science has taken on the seemingly insurmountable quest of investigating these physiological functions and finding a medical way to fight the ever growing obesity epidemic.
What happens in the Lab doesn't have to stay in the Lab!
Weight Loss Science Fact: Odd but True
Okay boys and girls, time to grab those love handles and hold on tight, because it’s another round of weight loss science fact. With a little luck [and a little reading] you won’t be holding them for long. With that let’s just jump right in, for those who are not in “the know” there are two types of fat: white adipose tissue and brown adipose tissue. The normal person’s body will preferentially choose white adipose tissue over brown. I’ll let you guess which one is the better of the two.
What happens in the Lab doesn't have to stay in the Lab!
Weight Loss Science Fiction: The Paleo Diet
You, yes you! Put down the Big Mac, come on you can do it. Now, let’s get back to our roots. It’s time to go hunter gatherer on your ass. In fact, you might as well dust off your loincloths and pull out your clubs, because paleo here we come.
What happens in the Lab doesn't have to stay in the Lab!
MORE Science Fact and Fiction Behind Fat Loss
I was shocked by the huge response to my first post on the science behind weight loss, so much so that I wanted to do a second post in the series if you will. With all the fad diets, weight loss schemes, and superfoods I will have plenty to write about that is for sure.
Just like part one in the series, I’m first going to go over some of the science fiction in fat loss. I hate pseudoscience and so before I go on a rant about that let’s just jump right in.
What happens in the Lab doesn't have to stay in the Lab!
Science Fact and Fiction behind Fat Loss
Do you have some of that unwanted belly fat? Do you get nervous that you will exceed the weight limit in an elevator? Do you want to eat everything in sight, but still lose the weight? Too bad, that is marketing, not science and if you want to lose the weight science can help, not so much the guy talking on the screen.
