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Posts tagged “pharmaceutical science

The relationship between low physical activity and psychotic symptoms

mental health exercise

mental health exercise

Physical activity can help reduce cardiovascular disease and premature mortality in people with psychological problems. However, there is limited data on exercise in people with serious mental disorders, especially from low- and middle-income countries. This study explored whether complying with the World Health Organization recommendations of 150 minutes of moderate-vigorous exercise per week is related to psychotic symptoms or the diagnosis of a psychosis.

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Why you’re stiff in the morning: Your body suppresses inflammation when you sleep at night

joint pain in the morning

joint pain in the morning

Feeling stiff first thing in the morning? It’s not your imagination, new research has found a protein created by the body’s “biological clock” that actively represses inflammatory pathways within the affected limbs during the night. This protein, called CRYPTOCHROME, has proven anti-inflammatory effects in cultured cells and presents new opportunities for the development of drugs that may be used to treat inflammatory diseases and conditions, such as arthritis.

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Could a popular painkiller hamper our ability to notice erors?

pain relief

pain relief

Pain, it’s a pain, it always seems to find ways to pop up when you least expect it, enter non-aspirin! Better known as acetaminophen, it has been known for centuries that is an effective painkiller. Since it is over the counter most people don’t give it a second thought, but according to a new study, it could also be impeding error-detection in the brain.

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Your brain has an altered response to desirable foods

Chocolate peanut butter sundae

Hungry? Well, let’s face it, that pizza looks much better than the salad. Don’t deny it salad lovers, we all know behind closed doors you look at plenty of food porn to satiate your desires. Understanding the motivations that drive us to eat is important when we talk about weight loss and how we attempt to structure diets. Now a new study shows that for overweight individuals, the brain responses differently to desirable foods., but hold that thought, because there is hope.

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Can exercise be replaced with a pill?

Can exercise be replaced with a pill?

Everyone knows that exercise improves health, and ongoing research continues to uncover increasingly detailed information on its benefits for metabolism, circulation, and improved functioning of organs such as the heart, brain, and liver. With this knowledge in hand, scientists may be better equipped to develop “exercise pills” that could mimic at least some of the beneficial effects of physical exercise on the body. But a review of current development efforts ponders whether such pills will achieve their potential therapeutic impact, at least in the near future.

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Genetic overlaps in autoimmune diseases may suggest common therapies

Genetic overlapping in multiple autoimmune diseases may suggest common therapies

Scientists who analyzed the genes involved in 10 autoimmune diseases that begin in childhood have discovered 22 genome-wide signals shared by two or more diseases. These shared gene sites may reveal potential new targets for treating many of these diseases, in some cases with existing drugs already available for non-autoimmune disorders.

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Cholesterol metabolism in immune cells linked to HIV progression, may lead to new therapy

How HIV spreads

This infographic shows how HIV spreads in the body. Image credit goes to: 2014 UPMC

Enhanced cholesterol metabolism in certain immune cells may help some people infected with HIV naturally control disease progression, according to new research. The findings provide a basis for potential development of new approaches to control HIV infection by regulating cellular cholesterol metabolism.

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Avocados may hold the answer to beating leukemia

Avocados and leukemia

Professor Paul Spagnuolo from the University of Waterloo has discovered a lipid in avocados that combats acute myeloid leukemia by targeting the root of the disease — leukemia stem cells. Worldwide, there are few drug treatments available to patients that target leukemia stem cells. Image credit goes to: University of Waterloo

Rich, creamy, nutritious and now cancer fighting. New research reveals that molecules derived from avocados could be effective in treating a form of cancer. Professor Paul Spagnuolo from the University of Waterloo has discovered a lipid in avocados that combats acute myeloid leukemia (AML) by targeting the root of the disease – leukemia stem cells. Worldwide, there are few drug treatments available to patients that target leukemia stem cells.

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Power of the media’s impact on medicine use revealed

Television doctors

More than 60,000 Australians are estimated to have reduced or discontinued their use of prescribed cholesterol-lowering statin medications following the airing of a two-part series critical of statins by ABC TV’s science program, Catalyst, a University of Sydney study reveals. The analysis of the Pharmaceutical Benefits Scheme medication records of 191,000 people revealed that there was an immediate impact after Catalyst was aired in October 2013, with 14,000 fewer people dispensed statins per week than expected.

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New drug can clear all psoriasis symptoms

psoriasis
Good news for anyone who has psoriasis, a University of Manchester led trial of a new drug has resulted in 40 percent of people showing a complete clearance of psoriatic plaques after 12 weeks of treatment and over 90 percent showing improvement. The research tested 2,500 people with psoriasis. Half were given a new drug – ixekizumab – either once every two or four weeks. The other half were given a placebo or a widely used drug for psoriasis called etanercept.

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Educating the immune system: A vaccine for allergies

Allergies and allergy sufferers

With the arrival of spring, millions of people have begun their annual ritual of sneezing and wheezing due to seasonal allergies. However, a Canadian research team  is bringing them hope with a potential vaccine that nudges the immune response away from developing allergies. The findings have major clinical implications since allergies and asthma are lifelong conditions that often start in childhood and for which there is presently no cure.

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US clinics avoiding government oversight of ‘stem cell’ treatments

The pitfalls of stem cell therapy

Clinics across the United States are advertising stem cell treatments that attempt to take advantage of what they perceive as exceptions in FDA regulations.The therapies in question are adipose-derived autologous stem cell treatments, in which fat cells are removed from a patient, broken down to separate components that purportedly contain stem cells, and are then reinjected into the same patient.

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