Mohamed Boutjdir, PhD, professor of medicine, cell biology, and physiology and pharmacology at SUNY Downstate Medical Center, has led a study with international collaborators identifying the mechanism by which patients with various autoimmune and connective tissue disorders may be at risk for life-threatening cardiac events if they take certain anti-histamine or anti-depressant medications. Dr. Boutjdir is also director of the Cardiac Research Program at VA New York Harbor Healthcare System.
Clinicians at Ludwig-Maximilians-Universitaet (LMU) in Munich have elucidated a mechanism involved in determining the lifespan of antibody-producing cells, and identified a promising new biomarker for monitoring autoimmune diseases like multiple sclerosis and lupus erythematosus.
With the arrival of spring, millions of people have begun their annual ritual of sneezing and wheezing due to seasonal allergies. However, a Canadian research team is bringing them hope with a potential vaccine that nudges the immune response away from developing allergies. The findings have major clinical implications since allergies and asthma are lifelong conditions that often start in childhood and for which there is presently no cure.
Papain is found naturally in papaya and is often referred to as a “plant-based pepsin” in reference to the digestive enzyme pepsin that is present in the stomach. Researchers looked at the effect of papain directly on the skin of mice as well as on skin cells in the petri dish. Skin consists of several layers joined via cellular connections called “tight junctions”. The project team showed that papain induces a breakdown of these cell-cell junctions. On the skin, papain results in a loss of the barrier function.
Methicillin-resistant Staphylococcus aureus (MRSA), an antibiotic-resistant superbug, can cause life-threatening skin, bloodstream and surgical site infections or pneumonia. It has been a tough battle finding ways to fight it and research now shows, cigarette smoke may make matters worse. The study shows that MRSA bacteria exposed to cigarette smoke become even more resistant to killing by the immune system.
Are you a woman? Do you find yourself allergic to everything, but water (and sometimes that is up for debate)? Worse, does your husband, boyfriend, or male friend seem to be impervious to any sort of allergy? Well I have good news and bad news, the good news is it isn’t you — or him. The bad news, is it’s your hormones…