What did you want to be when you grew up? Sometimes the question ends in hilarity, a dinosaur, a unicorn, or maybe some other type of animal. Sometimes it leads to dreams of a sci-fi future, deep space traveller, Mars colonist, maybe a superhero. Whatever the answer is, they all have something in common. No one dreams of being average, but the average exists because so many people fall into it. Most of us have our dreams die as the reality of our existence becomes clear. I say fuck that, dream big until your last breath, why not?(more…)
What a combo breaker, two years of dedication and daily blogging down the toilet because the government was trying extremely hard to kill me. I’m not mad, just disappointed, okay I’m very mad (in the government stuff, not my streak that’s not a big issue). Technically I’m not through the storm quite yet, the power could still go back out, but I have had power longer now than I have in the past few days. Long enough to write a quick update anyway.(more…)
“Two roads diverged in a yellow wood…” starts Frost in a poem that most people are at least familiar with, but typically is misnamed. The poem is typically identified as, “The Road Less Traveled”. This makes sense because the poem talks about the thought process behind why he chose the road less traveled and that it was worth it. That’s not the name of the poem though.(more…)
Yet again, here we are. We shouldn’t need to do this, but people are quick to kill off grandpa and a whole lot of other people in the process, so once again we need to use uncommon sense. Stay home. Seriously, don’t visit family, there are plenty of other holidays post pandemic to celebrate, for now just keep you, your family, and all the families your family comes in contact with safe. Stay the fuck home.(more…)
Every sunday without fail I make my list of tasks for the week ahead. Some of them are automated and repeat as needed, but most are specific to that week so I need to go in manually and add them. It’s nice to have everything written down in one place, in order, with times and reminders. I don’t have to stress out about remembering everything when I have a nice app on my phone that keeps me informed. Unfortunately there is a downside…(more…)
We’re post-op day 2 so far and the word of the day is ouch. I don’t know that I went into detail about the surgery I was having, I mean I’ve been out of it these past couple of days since the surgery. It was a spinal cord surgery, there was some scar tissue that was giving me some trouble and they went in bilaterally (both sides of the spine) to remove it. That was… fun.(more…)
Well I had a surgery yesterday and it didn’t go as smoothly as I hoped. I’m home now thankfully, but there were some… complications and it could be for a lot of reasons, but I’ll cover the most likely issue and then go and rest some more.(more…)
Well today is the day. I just checked in and ready for surgery. For those of you who follow along, this isn’t the first surgery I’ve had. I’ve had two surgeries a year for the past four years. It’s a lot, but each one offers the promise of a slightly better life.(more…)
The day hasn’t even started yet, but it’s a bad day. No I’m not ripping off a children’s book with a similar, if not more hyperbolic name, it’s seriously going to be a bad day. You may be wondering how I know, well this time of the year is always rough for me. A lot of bad things happened that I don’t have the space, mental capacity, or time to talk about. Today is a bad day.(more…)
Some days there’s just so much going on it’s hard to figure out what to write about. Daily writing is hard because some days you have 50 things you want to share and some days you can’t figure out a single thing that would be interesting to write about. While I have a million things to do, none of them are new and interesting enough to share. So today I’ll let you in on my secret.(more…)
Sunday means getting ready for the rest of the week and what a week it will be. In my Co-PI’s lab we typically have a steady stream of people coming and going for experiments, this week (and probably next) it will be a flood. We’re trying to make my main-PI happy.(more…)
Why does everything happen at once? I mean you’re minding your own business and bam, suddenly you have a million things to get done. One minute you’re on top of things, the next you don’t know how you’re going to get it all done. I’m somewhere in the middle of all that right now. I’ve managed to get most/all the things I needed to get done, but not without some new things popping up.(more…)
Well it’s Thursday and by looking at my list of things I need to get done, I wish it was still Monday. There’s been a few setbacks the past couple of days. My data processing is going well, but not much else has been accomplished because of an incident that happened a few days ago. It’s not a fun time…(more…)
Well if things weren’t bad enough as it is with my own little world, we get to add car troubles to the list. Dealing with issues like this during normal times isn’t so bad, besides the bill that is, but this isn’t normal times. Nope, we’re dealing with a pandemic, school is about to start, and to top it off, I firmly do not have the money to fix the damn car, what’s a guy to do?
Yesterday I told the story of how we got to this point, a long two year journey and next week I finally get to take the next step. It’s exciting, but it also means because of my flare-up, I’m behind on what I need to do to be ready. Not to worry though, I’m taking it slow so I don’t make whatever I have worse. What goes into an experiment like this? I’m glad you asked!
Okay I’ve got an experiment update today and I’m really excited to share because it feels real finally. I know I already wrote about some of this, but when I reread my previous post, it felt disjointed so let’s go over how we got here and what’s coming. I’m excited, are you excited? I’m excited!
Anger, after thinking about it, it was anger I felt. Not at anyone in particular, but I was angry and hurt and a lot of other similar emotions, but I was angry most of all. People kept letting me down and it took a chance twitter conversation for me to realize why I was yet again left feeling so fucking angry.
Well today despite feeling like refried dog poop I have to go do experiments. It’s part of the job and to be honest I want to do it even though I feel like dried monkey vomit. I could go on, but you get the picture. I do have some more good news not related to yesterday’s news. So that is the conversation for the day.
I was awarded something, we’ll get to the what shortly. I was awarded something and I was excited because it felt like validation of my work. It felt good to have people take notice of my accomplishments. There are precious few times in my life where I’ve got to feel like someone selected me out of a group as exceptional. Here I was being nominated for something! I was walking in the clouds. I could do anything, be ANYTHING.
Today is a mash of things, because frankly I still am not feeling good. My the scaly bits on my hands, face, and apparently elbows (missed that one until last night) haven’t gotten worse (yay), but they haven’t gotten better either (boo). On one hand it’s a realization that whatever is wrong with me was worse than I had thought, on the other, the world still moves forward and unfortunately I have work to do, so what’s a guy to do?
It’s going to sound like depression. I realize that as we dive into today. I don’t normally do this, but I’m rewriting this intro because I know what it sounds like. It’s not that, this is something else and it worries me. I know depression, I’m good friends with depression, this is something different so don’t tell me it’s depression, it’s not I promise. It just happens to be worse than I can ever remember right as I’m dealing with the worst flare up [of whatever I have going on] in my entire life, so it couldn’t be a coincidence … could it?
Well today is day one of three for wrapping up our undergrad/high school research experience. We had a group of about 50 I think, just in our lab and a good portion of them were high school students. Because we’re living in a pandemic, this was all done virtually! Today we get the first glimpse into how we did as mentors.
It will pass, it always does, but for now I feel like I’ve been punched in the gut. I don’t enjoy the feeling of being average, or more than likely below average. It means I have to do twice the work for half the result. I see genuine greatness and know that no matter how hard I try, that will always be out of reach for me. What do you do when you want something so bad you would die to get it and you know you will never reach your goal?
It was bound to happen eventually. We all knew it would, but we didn’t expect it to fail in such a spectacular manner. That is to say, all at once. One of the people I’m mentoring checked out some lab equipment since we had come up with a way to do experiments from the comfort (see: safety) of her home. That was the plan anyway…
I have a lot of disabilities. Some are more debilitating than others for sure, most are just annoyances or give me weird quirks that people sometimes are frustrated with, other times get a laugh from. For the past few days I’ve been dealing with a flare up so bad I’ve never experienced anything like it in my life. It was a painful reminder that I was in fact stressed.
I’ve probably mentioned this before, but I feel stuck. With the pandemic going on and the protests (Which are still happening!) I don’t feel like there has been any forward movement in anything I’ve been involved with. I hate feeling like this, it’s so frustrating especially when I feel like I’m drowning in work to be done.
Look around, we’re drowning in information. It’s an overload, we literally were not made to absorb this much information all at once. News stories bombard us with new bits of it. Social media is full of it. Ads promise you forbidden knowledge with this one weird trick. It’s no surprise it’s hard to tell what’s real.
With everything going on it’s been tough to write about just one topic. When I started 365 days, I started it with the intention of highlighting my struggles and trials through one full year of my PhD with the idea that I may (or may not) keep going for the duration of my PhD process. Then COVID hit, Black lives matter protests took off (finally), and I had the realization that I, like most people, am more than just my studies.
Well I got word yesterday that the coronavirus found its way onto an aircraft carrier. For anyone who’s never seen one in person, because the pictures don’t do it justice, these things are huge. Think floating cities with the crew size to match. Inside an aircraft carrier, there are roughly 3,000+ people who work, live, and maintain the ship. The one in question, the U.S.S. Theodore Roosevelt has over 4,000 crew members and those are just the ones that need to be quarantined. This is bad for a lot of reasons. For those of you who haven’t served in the military, I’ll explain.
For the past week we have been utilizing online resources so that classes can continue while we are all social distancing. While this is means that we mostly use Zoom, we also have message boards and other resources that we can use. However, these resources are sometimes a poor substitute for in person classes. This is especially apparent when we have certain assignments for the class, such as a group presentation.
Well it’s been two weeks since the last critical review so it’s that time again. As usual, my PI gets a copy and so do all of you. Since I’ve done several of these now (this is number six) I have a category just for these reviews called critical reviews. This is a really new study which tries to help tease apart what we are actually stimulating when we apply transcutaneous spinal stimulation. I think it’s a super interesting paper and I hope you do as well.
It was bound to happen, with the COVID-19 outbreak, my entire schedule has been shifting faster than I can keep up with it. I was going to force myself to write today, but I need a break. I’m exhausted both mentally and physically. There is a possibility I won’t be getting my stipend from the school this month, even though I’m still working, and I have assignments due soon, so I can’t dedicate the normal hour or so I would writing.
Friendly reminder, wash your hands, don’t touch your face, and practice social distancing. Even if you’re healthy, you can infect people that are not healthy or worse, people who work with others who are not healthy. Don’t be selfish! It may seem stupid now, but if we don’t do these things then it will get a lot worse and no one wants that. We can get through this if we all work together.
Well after our short break yesterday with my biweekly review paper, it’s back to the know your spinal cord series and we’re on day fifty-two! If you’re here for the first time, you can find the posts in this mini-series in the neuroanatomy category. We’ve taken a few twists and turns since we’ve started the series, but we’ve covered way more than I originally planned. We’ve covered how transcutaneous spinal cord stimulation is thought to work, that post focused on the type of spinal cord stimulation I’m researching. However, there are other ways to stimulate the cord. Transcutaneous spinal direct current stimulation (tsDCS) is a different way to stimulate and today we will talk about the difference.
Day 210: Review – Cervical trans-spinal direct current stimulation: a modelling-experimental approach
I lied! I did know what today was going to be on, it’s the fifth critical review paper. Since my PI gets a copy, so do you! To be honest, I need to create a category for these reviews (Update: I did make a category, Critical reviews), but for now, my first looking at elbow spinal stretch reflexes is here. My second where I review modulating spinal cord excitability with a static magnetic field here. The third where I review modulating the H-reflex while walking in spinal cord injury populations. Lastly, my fourth on Motoneuron excitability during voluntary muscle activity in a spinal cord injury population can be found here. That said, let’s take a look at my latest review.
It’s day fifty-one of knowing your spinal cord! For those of you who just found us, fear not we have all these posts in reverse chronological order listed in our neuroanatomy category. For everyone else, lately we’ve been talking about glial cells. This came about from the post on glial scarring which made me realize we should probably define glia. There are four types of glial cells found in the spinal cord (that we know of) we’ve covered three of them already and today we are talking about the last kind, the microglia.
We made it to yet another milestone, day fifty in our know your spinal cord series! As usual, you can find each and every one of these posts neatly organized in reverse chronological order using our neuroanatomy category. For the past couple of posts, we’ve introduced the types of glial cells, probably a bit poorly, but they are just so complex we can only really focus on a few of the functions. Needless to say they are very important cells. Today we are talking about the third (of four) types of glial cells found in the spinal cord (and brain), that is the ependymocyte. Let’s take a look.
Day forty-nine in the spinal cord series! You can find all the posts in this series in our super useful neuroanatomy category. A couple of posts back we introduced glial scarring, one of the problems we need to overcome to help people with spinal cord injuries. That led to the realization that we needed to introduce the glial cells, so yesterday we covered the oligodendrocytes and today we are talking about the astrocyte. Now that we have some background of how we got here, let’s introduce today’s topic.
We made it to day forty-eight! As always, the neuroanatomy category will help you find each and every post in the spinal cord series. It’s all really good stuff! We mentioned yesterday that this was coming, we’re going to do a quick breakdown of the types of glial cells just to make understanding the glial scarring post easier. Plus it helps to understand the functions of glial cells in general when we talk about things that could go wrong. With that, let’s get into oligodendrocytes!
Here we are at day forty-seven of spinal cord posts. We are definitely wrapping up our series sad to say, maybe we can get to day fifty, that would be a nice round number to stop at. For those of you who want to read all the other posts, the neuroanatomy category has everything in reverse chronological order and will teach you everything from the medullary pyramids, the cauda equina, and all the stuff in between. Today we are talking about glial scarring and why it’s such a problem a topic I realized we should touch on after talking about the problems with invasive spinal stimulation methods yesterday.
It’s day forty-six in our spinal cord series. While we’re nearing the end (maybe), there are still a few things to cover. First, if you’re new, you can find all of the posts in the neuroanatomy category for when you need a quick spinal cord fix. I’ve been debating about this post for some time, but I figure we might as well cover it since we’re here. Today we are going to talk briefly about invasive spinal stimulation and what the future might hold.
Day forty-five of the know your spinal cord series is here! With so many posts, you may be wondering how to find them all. Fear not, we have a super helpful neuroanatomy category for all your spinal cord needs. For the past few posts we’ve looked at some very interesting tools to probe the spinal cord. We’ve seen that there are quite a few ways we can go about it, but more importantly they all tell us something slightly different. Today we are looking at the product of that stimulation, the compound action potential.
Welcome to day forty-four in the know your spinal cord series! As usual all of our posts are in a super easy to find neuroanatomy category. Now that we’ve covered our into into diagnostic tools to probe the spinal cord, let’s look at some of the ways we are working to help treat spinal cord injuries. Today we’re looking at a heavy hitter so to speak and something my research is focused on, transcutaneous spinal stimulation (TSS). Let’s take a look!
We’ve made it to day forty-three of our know your spinal cord series! While that is a lot of posts, we’ve made it super simple for you to find all of them with our neuroanatomy category. Lately, we’ve looked at several different tools in our spinal cord probing toolbox. We’ve seen all sorts of different ways to create a response, but we are still missing one important tool for our exploration into the unknown spinal cord world and that is what we are going to talk about today!
We’re back again with day forty-two of spinal cord knowledge series and day 200 in our 365 days of academia series! A friendly reminder that you can find each and every one of these posts in our very helpful neuroanatomy category. Yesterday we looked at motor evoked potentials, or electrical pulses that we create which travel from the brain to the muscles. Today we are looking at the almost reverse, signals we create originating in the peripheral nerves and arriving at the somatosensory cortex of the brain.
Day forty-one in the know your spinal cord series. While the number of posts is going up, we made them easy to find by using our awesome neuroanatomy category! Maybe we did this a bit backwards, but it’s our series and this was the order we did it in. Yesterday we covered cervicomedullary motor evoked potentials, which is a subset of what we will be covering today. So again, slightly out of order, but hey let’s look at motor evoked potentials.
We made it, day forty in the know your spinal cord series! I honestly didn’t think we would get this far into things, but here we are. As per usual, if you’re new you can find all of the posts in this series in our super helpful neuroanatomy category! For the rest of you, or the ones interested in this topic, today we are looking at yet another tool in uncovering the secrets of the spinal cord.
It’s day thirty-nine of our know your spinal cord series and we’re only touching the surface (so to speak)! If you’re just joining us, then welcome! You can find all of our spinal cord knowledge in the handy neuroanatomy category. Well as these things typically happen, yesterday brought up an interesting gap in our knowledge base. While I introduced the H-reflex, we never talked about the F-wave! So of course yesterday’s post probably left some of you scratching your head as to what an F-wave even is, fear not we’re going to clear that up today!
Day 196: Review – Changes in Motoneuron Excitability during Voluntary Muscle Activity in Humans with Spinal Cord Injury
A little detour from our spinal cord series for my fourth critical review paper. As usual, my PI get a copy and so do all of you! You can read my first looking at elbow spinal stretch reflexes here. My second where I review modulating spinal cord excitability with a static magnetic field here. Or the third where I review modulating the H-reflex while walking in spinal cord injury populations. Today is an interesting paper on motoneuron excitability while walking in spinal cord injury populations. It’s a really cool paper, so here’s my review.
Welcome to day thirty-eight in the know your spinal cord series. As always, you can find the entire know your spinal cord series exclusively listed under our neuroanatomy category. We’ve amassed quite a bit of spinal information and I’ve gotten into more detail than I originally planned, which is part of the reason why we are going back and covering some of the things we skipped over. Today is one of those topics, we will be talking about the spinotectal tract, not to be confused with the tectospinal tract, which we already covered.
We’ve arrived at day thirty-seven in the spinal cord series and we’re still covering new ground. You can find all of our sweet spinal cord action in the neuroanatomy category, which at this point is pretty extensive for a high-level look. Yesterday we talked about the reticulospinal tracts so today we are talking about the sister tract, the spinoreticular tract. Are they related, or is it all just in the name?