We're a little crazy, about science!

Posts tagged “learning

Dear data gods

We have offered our typical sacrifice of blood, sweat, and some might even say excessive amounts of tears. Yet clearly we have offended you and we are not sure how or why. We ask that you forgive our ignorance and help us understand how we can fix this. We are humbled and sorry, we should not seek higher truths, yet we must continue.

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Mad dash to the OR

Today has been a day! The trick with doing research in the OR is that the schedule for the surgeries don’t get finalized until the day before and sometimes even then things change at the last minute. I’m not sure when the schedule was finalized or if anything changed, but this morning I got a text that threw everything out of order. The best laid plans of mice and men…

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Writing rush

Well today I will be spending the bulk of my time editing a journal paper that needs some work. Okay a lot of work, it’s not great, but I feel like it’s a case of switching fields. Something I know all too well when I jumped from mechanical engineering to neuroengineering. I try to be polite when editing because it’s stressful enough as it is. However, it’s important to remember that it’s the paper being critiqued, not you.

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The fourth OR experiment

It’s official! We have experiment number four coming in two days. I’m excited about another attempt to collect data and to answer about a dozen interesting questions since we just keep tacking on stuff to look at when we go in. I’m not even joking, the experiment list keeps growing because the opportunity is unique and they don’t add significant amounts of time to the main experiment we’re doing.

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Another year of NDSEG

Yesterday was the last day to apply for the NDSEG fellowship and if the traffic to my fellowship tips post (here) is any indication about the number of people who applied, this year is going to be competitive. It’s bittersweet for me, because this is the first year I won’t be applying. Mostly because I am no longer eligible for it, but also because I literally have more funding than I know what to do with.

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Sometimes things get cancelled

Today was a big day. We got the equipment ready, the patient consented, and everyone on the clinical side of things was on the same page we were on. Things were going well. Surprisingly well in fact, that should’ve been the first sign something was going to go wrong. This time it wasn’t our fault though! Sometimes you just can’t catch a break, so maybe next time.

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Off to the OR!

Tomorrow is the big day, our second experiment and while I’m a little nervous, I’m also excited to see what we can do. Last time around we had some issues… okay a lot of issues, but that’s because it was the first time we’ve ever tried something like this. This time around we worked with the team that will be in the OR with us so we know what they are doing and this time they know what we are doing. Basically we’re aiming for a whole lot less drama and a whole lot more useable data, meaning any usable data!

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DIY Research

When I say arts and crafts projects, I really do mean there is art involved.

Working in a big fancy hospital research lab means I get access to all sorts of very expensive, very cool equipment that I wouldn’t be able to use normally. Things that I take great pains not to break because, well… it’s not cheap. If we need something, we order it and the process is surprisingly fast considering the amount of paperwork that goes into placing an order. However, on occasion there are no ready pieces of equipment that I can just use for an experiment or we don’t know that the big expensive piece of equipment that we’re looking at is the thing we actually need. So what other options do we have? Spoiler, it’s arts and crafts time.

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Experiments from the OR

The last place you would expect to see me doing non-invasive research would be the operating room. Surgery, even the minor stuff, can be very invasive, but that doesn’t mean we can’t collaborate and combine our techniques. Of course this is the first time anyone in the hospital has tried to collaborate like this (that we know of anyway) so there’s bound to be some growing pains. Luckily we’re about to go into our second real attempt at this and I think we’ve worked out all the problems.

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The road to nowhere

Get it in writing. It was the advice I gave hospital-PI when he told me he got an offer from another hospital. Get it in writing. It was a phrase drilled into me by the military where less than honest recruiters would promise one thing, but deliver something else. I learned early on that your word is worthless, opinions change, memories fade, and you’re left with people who are upset because neither no one thought to write it down so everyone would be on the same page. Some lessons are learned the hard way I guess.

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Journal paper number three is submitted!

Finally checking a few things off my list, now this will probably come back to me for edits in the next few weeks/months, but paper number three has been submitted for review! As with the last few papers, I think we can go through the process of how we got to this point and I can explain what happens now for those who’ve never submitted a journal paper before. I’m really excited, so let’s talk about the long road leading to this point.

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The confusing road to my dissertation

I’m very lost at the moment about what the next step would be in my degree. I mean I know what the next step is, my dissertation proposal, the problem is that there’s now a rather large wrench thrown into the mix and I’m not sure what to do. Honestly it would be so much easier to just give up on my degree and go work like I’m doing now, it really would, but after three full years in the program and a decade of schooling to get to that point, I don’t want to stop short. Which means once again I’m faced with an impossible choice and no matter what I decide I feel like someone is going to get hurt.

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Dissertation crossroads

It had to happen sooner or later, I have too many PI’s, and it was bound to cause some chaos in my life. The short version, in case you don’t want the longer one, is that I need to decide if my dissertation project is really the way I want to go about my degree. I have some options for what I want to do for my dissertation and my hospital-PI has offered several alternatives to the original path I was planning. It’s a tempting offer too, I just don’t know which one would be the better option or if there really is a choice here since I’ve technically already committed to the other project.

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Winter conference season

It’s that time of the year again! Every six months or so we have an influx of conferences and what not that happens pretty routinely in winter then again in the spring. Thanks to COVID still being a thing — get vaccinated people — we’re either going fully virtual, or since one of our events this year is smaller, we’re taking precautions to keep people socially distanced and masked (since it’s a hospital organized event, we’re all already vaccinated). Tomorrow is the first event of the season and I’m giving a short (five minute) presentation on the work I did for this particular group.

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The surgical scramble!

Today was an… interesting day. Saturday I mentioned that today I would be in the OR again, it feels like I’ve been living there for a bit now and I have to say I’m enjoying it, but things were a little more hectic than I had originally anticipated. I had arranged for everything to be ready well before the surgery took place, but as it turns out that wasn’t what happened and I was left to scramble in order to get everything working.

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Papers, experiments, and the week ahead

It’s going to be a busy week and the weekend has only just started. While I plan on taking some time to myself this weekend, I am going to be prepping for the week ahead today since tomorrow is halloween. There’s a lot of interesting stuff happening this week, so today I want to round up all the odds and ends to give you an idea of what the week will look like, but also to help me organize my thoughts as I get ready.

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Award interview and project update

Yesterday was the big interview between my school-PI, surgeon-PI, and myself. It was significantly longer than I expected it to be, but it was also strangely focused on me. That was completely unexpected, so I felt a little awkward, but I did it and we’re all very excited to start my project. I have some thoughts about the interview, but I also realized I haven’t really spoke about my “super secret” technique in a while so some of the newer followers may not even know what I’m talking about (don’t worry, it’s a super secret).

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Smile for the camera

Today is photo day! What is photo day you may ask? Well it’s the day we take pictures. Okay, probably a little brief, today is the day that we’re meeting with the lab and school public relations team to release a joint statement about our new award. It’s the first award for our new collaborator (surgical-PI, who I still need to find a better pseudonym for) since he just started his new lab at the hospital at the beginning of the year. While it’s not a major award (dollar amount), we tend to celebrate these things anyway, so we’re taking pictures together, surgical-PI is getting a tour of the school lab, and we’re going to get interviewed about the details of the project.

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Another award?!

Yet again I’ve managed to slip through the cracks, or maybe the standards were just that low. Whatever the reason, I’ve been selected to share my science in the form of a podium presentation. Yep I was awarded a spot to present my work at an upcoming event I’m required to attend (luckily it’s a masked event, because we’re all medical professionals) so I get to give a supposedly “fun” elevator pitch of my work. Just a few weeks away, I have to figure out what I want to say and how I want to share it. The issue isn’t so much that I’m speaking in front of a group (that isn’t on my computer), the challenge is the state of the project.

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Outreach while recovering (or why I should stop volunteering for stuff)

Basically what I look like at the moment… you know, give or take.

I got bullied into it. Okay, maybe I felt guilty. I don’t know! Whatever the reason a few weeks ago my school-PI emailed several of us asking if we would be willing to do a virtual outreach event today. Somehow, despite just having surgery, I am the one doing it. Since this blog is just as much for me as it is for all of you, this is a cautionary tail and a reminder to myself to just say no sometimes.

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The award announcement

Well it’s official, my project got funded. It’s a little hollow since we knew ahead of time that it was going to be awarded, but now that it’s official we can make a big deal about it. By we I mean my school-PI and our collaborator, who I guess is technically my latest Co-PI, so now I have three PI’s and you thought my life was complicated enough already, didn’t you?

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The two year countdown

Yesterday was exhausting! In the end though I had a meeting with my school-PI (I think that’s as good a nickname as any) and we discussed what my timeline is and when I see myself graduating. A lot of what we discussed revolved around the funding we just got and the fact that I’ve just taken a new job doing research full-time in a clinical (see: hospital) setting. The talk went well, he’s been supportive of the fact that I took this job and even though it’s caused some friction between school-PI and hospital-PI (formerly main-PI and Co-PI respectively) things are settling down some and I’m hoping to find some minor and probably temporary stability in life.

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Planning my dissertation

The word of the day is apocalypse, since that’s pretty much what I feel like is happening lately.

It will still be awhile before I can graduate. I’ve got roughly two years left (more if I’m unlucky, so definitely more) before I’m done and today I’ll be meeting with my school PI, previously my main-PI, but now that I’m working for my Co-PI I need to come up with new titles, to discuss my life’s work. Or at least my PhD life’s work, since this is a conversation overdue, but now needs to happen because of some good news we recently got.

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Part three, extreme PC modding!

Where we are at, for the moment.

It’s no secret, it’s been a hell of a week for me. To help distract me (unsuccessfully) I decided to do some of the major mods to the PC that needed to happen in order to get everything the way I want it for the final assembly. I’m hoping tomorrow will be that day, but there are still (STILL) parts I’m waiting on, so it may be a photo finish. If not, well I can always finish is during the week or next weekend (probably).

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Day one of the computer rebuild

That giant blob on the right? That’s my computer.

Well today’s the day I crack open the computer case and get to work on fixing my desktop computer. Since I have not popped anything open yet, I want to talk a bit more about the plan going in, how I am going to do things, why you should do it too if that kind of thing sounds fun to you, and why I selected some of the things I did.

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Third paper updates

Yes, we’re switching focus from my mental health to other things today. Mostly because I feel like I’m just repeating myself in different ways, so instead we can talk about the forward progress I’ve made in my writings. This will be journal paper number three and if my Co-PI is right, we’ll be submitting it early next week!

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So you’re nervous about the COVID vaccine

Welcome. First I guess we should make it clear, I’m vaccinated, I’ve been vaccinated, and I got vaccinated early on. If you’re reading this and not a regular around here, then you’re probably looking for some good information about the vaccine to help assuage your fears. The good news is that if you’re here you probably want someone to tell you that it’s okay, that the vaccine is safe, and that you should get it. Well I’m happy to do that for you.

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Yet more papers!!

Well if it isn’t the week of every single thing that needs to be written needs to be done today, I don’t know what week it is. For those keeping score, I’ve successfully had one paper accepted for publication, had a random update and submitted a second paper for publication, and now I’m working on two other papers while I’m waiting to hear back about a third. What a week.

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It took multiple days to write a single paragraph and other odd, but true tales

Maybe I’m just weird. Okay, I’m definitely weird, but that’s not the point. It’s been three full years since I started my PhD and I’m still pretty self-conscious about idiosyncrasies, or at least the ones I’m aware of. Some of them aren’t a big issue, some of them may just be preferences, some of them just could be from the way I was raised. Whatever the reason, I thought it would be fun, or at least funny, to share some of the weird things I’ve done.

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Paper juggling

With one paper officially off my plate and another in limbo (not sure what’s going on with that one!) I have two papers that need my attention and they need it NOW! Both papers need to be finished ASAP and one of them in particular needs to get done faster than that, as in today if possible. That’s going to be hard, but since I work better with a plan I figure we can get into how and why I’m forced to work on so many papers!

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The transition to clinical research

Today should be interesting… it’s my onboarding appointment, which is one of the last steps I need to complete to be hired at the hospital. There’s a lot going on in life at the moment, some of which is personal so I won’t be sharing that here, but let’s just say everything has been incredibly stressful. Oh and since I need to get the appointment done this week if I want to start on time, this was the last day I can get it done.

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On to the next paper

With one of my four papers finished and finally accepted for publication (yay!) it’s time to switch gears to getting the others done. That said, progress has been made and I’m stuck swapping between two papers at the same time since both need to be done and submitted soon. There’s some analysis that needs to happen, figures to be made, code to be written, just a lot of loose ends to tie up.

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PhD proposal prep

Well I’ve finally made it to the next milestone in my PhD. I’m now at the point where I can do my proposal defense. It shouldn’t be too bad, but there’s a lot involved between now and then that needs to happen including coming to some sort of an agreement between my two PI’s about what exactly the project will consist of. Since I had no idea what getting a PhD entailed when I started, I’m assuming at least some of you have no idea what’s going on so let’s go over how we got here and what I’m getting ready to do.

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Success! Journal paper 1 of 4

Psst, hey you! I got good news! I’ve officially had my first journal paper accepted for publication! I’m literally crying I’m so happy right now. My inbox has been flooded by emails from my collaborators congratulating everyone on this. It’s been a long, hard, and often painful journey, but I’ve finally, FINALLY, gotten something finished once and for all. Since this is the end of the story, let’s tell it from the beginning, one last time, so you know how we got here.

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The week ahead

Well the next two weeks are shaping up to be interesting. I’ve got a lot of the onboarding stuff to get out of the way for my new job (yay!) and I’m still juggling two different papers basically full-time. Considering those two things are really the only stuff on my plate at the moment things feel pretty good, sort of anyway. There’s still a lot of mental health stuff going on and I’m just feeling overwhelmed with the choices I’ve made so far. So what’s the game plan for the week look like? Let’s talk about it.

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The resubmission!

Well we’ve crossed that milestone… yet again. I’ve submitted the third version of a paper I’ve been working on… for years now. Yeah, they can take a while and with COVID, things took even longer. So what happens now and what the heck is going on? Since it’s it’s already been an incredibly busy day, let’s recap the journey this paper has been on and how we got to the latest and (hopefully) last submission of my paper!

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I wanted to be a scientist

What did five-year-old you want to be when you grew up? I see this question pop up on twitter every so often, or rather the question is often would five-year old you be proud of where you are now. I think it’s hard to judge your five-year-old self when you’re an adult because the world looks a whole lot less polished and magical when you’re an adult. In my experience as you transition to an adult that magic and wonder is slowly replaced with dread, anxiety, and mostly doubt. Imposter syndrome is a real thing that many people, including myself, deal with.

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The art in science

One of the easiest ways to turn even the most advanced scientific paper into something accessible is through carefully crafted figure design. Figures are a way to tell a story, but to also capture the readers imagination. The difference between a scientific figure and a drawing from a story is really just the difference in the information you are conveying. However, as is the case with most things in the world, a “good” figure is in the eye of the beholder.

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On trying something new

As a grad student the work/life balance tends to blur. I actually do most of my work on the weekends and tend to try to take time during the week for myself. This works best for me because weekends are typically when no one needs me to physically be somewhere, so I can get into the correct headspace to do some work. This weekend was a busy one, and my Co-PI had some ideas about one of the papers I’m working on that required my full attention. He also wants me to do something I’ve never done before, so let’s talk about trying something new!

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Non-invasive study of the brain

Art by the incredible Greg Dunn (I REALLY!!! wish I could afford his work!)

Non-invasive research is difficult, especially when you’re working with something as complicated as the brain. Imagine being at a pro sports game outside the stadium and trying to figure out what’s going on inside just by listening. I’m constantly in awe that we can record activity from the brain without breaking the skin, it’s like magic. However, it’s still difficult and not without controversy.

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A small success

It was a leap of faith. There were no good choices, but it was the best of options in a string of bad options. I could either work full time in my main-PI’s lab, pulling me away from the clinical research I love, or I could take a job in my Co-PI’s lab. The catch was to take the job with my Co-PI I would have to apply, wait, and go through the onboarding process. That would mean I wouldn’t be getting paid, which would be okay for a few weeks, but longer and I could be in trouble. Nothing is finished yet, but I’ve gotten some good news.

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Minor revisions

Ah, just when I thought I didn’t have to worry about one of the multitudes of papers that I’m working on, it comes right back. This is the journal paper I wrote for one of my classes, which looks to be about ready for acceptance. There were some minor revisions that we were asked to make, but as of ten minutes or so ago I’ve addressed all of them. I think… it will probably be another round of edits with our co-authors to make sure everyone is happy with what we’ve done. Maybe? I’m not even sure at this point.

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A game of cat and mouse

pov: you’re trying to do some work and your cat is not happy with your progress.

Cats, you bring them into your home and suddenly you’re the guest. I can’t complain my two furry monsters always want my attention and it can’t hurt to be wanted, but it definitely and almost exclusively happens at the worst possible times ever. Namely when I’m in the middle of doing work on my computer. So I’ve gotten into the habit of taking a photo or two of them when it happens. Only on occasion, only when they are being particularly obnoxious, but after looking back I’ve got quite the collection of photos. I figure I would share the wealth.

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The voracity for exploration

Humans have set foot on the moon, multiple times in fact. We didn’t go once, we went six different times. Six times. That feels both like an incredibly large number and an incredibly tiny number all at the same time. For you and me it probably doesn’t feel like anything special, but for the people who’ve done it, they KNOW it was life altering. They told us so and it’s a shame that in my lifetime I will probably never set foot on another planet and have the chance to feel so… insignificant.

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Controlled chaos

Life has been pretty messy lately. Not just because of the pandemic, but that is definitely not helping anything right now. I’ve got papers due, I’m making a job change, and the wildest part is that my Co-PI may be leaving so I’m not even sure the job I’m changing to will still be there after the end of the year. That doesn’t include the outside factors, car issues, home issues, health issues. Those are all there too, but mostly right now I’m concerned about work related stuff and I realized that for the past few months it’s just been controlled chaos.

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Education in a pandemic

Well the term is officially underway and with it comes in person classes! Because if there’s one thing a life is worth, it’s money and there’s money to be made by forcing you into the classroom. Yes the world has changed and we adapted with it, somewhat, but even with hospitals on the verge of collapse (again) we’re given the unequivocal message, “We’re going back to normal!” from schools. There’s nothing normal about it, but the economy is built on the backs of the people, so I guess, in a way, we are returning to normal.

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Multi-paper madness!

HELLLP! I’m doing way too much writing and it’s the scientific kind, which is to say soul sucking! Okay, it’s not that bad, but for the past month it’s been a mad rush to get several different papers written. Today I plan to go over all the papers I’m working on, the progress I’ve made, and why I really hope I’ll never have this happen again. Far too much writing! It has to end eventually though, right?

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The end of summer

It’s officially the start of the new school year. I’ve got a lot of anxiety headed into this year, but not for me, for everyone else. This year will be the first year that I’m completely finished with my degree requirements, now I just need to do my research so there’s no real need for me to be inside a packed classroom with others who may or may not be wearing masks or are vaccinated. So instead of being super depressing, let’s look at some of the highlights from this summer and what is just around the corner.

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A small job update

It’s not a straight line to the finish, that’s for sure.

A week ago almost exactly I did something incredibly stupid. Okay, I did it because I really want it, but there’s a chance it could blow up in my face, I’m going into research full-time to help pay for my PhD. Now, I’m not paying for my PhD, that is never a good option. Instead the hospital I will be working at will be paying for my PhD now and I will get paid better while I wrap up the last two years or so of my degree (more here).

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Analysis fails

I’m an idiot. So for the past few weeks I’ve been working with our super fun new dataset! Like a big kid, I did the statistics, made the checks to ensure that the assumptions held, then got my result. Everything was going well until I realized there was a typo (here) in my code. Well it turns out that wasn’t my only problem, but everything should be fixed now… should.

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