There are plenty of reasons it’s important to maintain a healthy weight, and now you can add one more to the list: It may be good for your brain. Researchers have found that having a higher body mass index, or BMI, can negatively impact cognitive functioning in older adults.
Tauopathies are a group of neurodegenerative disorders, including Alzheimer’s disease that are characterized by the deposition of aggregates of the tau protein inside brain cells. A new study reveals that the cutting of tau by an enzyme called caspase-2 may play a critical role in the disordered brain circuit function that occurs in these diseases.
Among a group of older women, self-reported caffeine consumption of more than 261 mg per day was associated with a 36 percent reduction in the risk of incident dementia over 10 years of follow-up. This level is equivalent to two to three 8-oz cups of coffee per day, five to six 8-oz cups of black tea, or seven to eight 12-ounce cans of cola.
We all know that we can quickly lose cardiovascular endurance if we stop exercising for a few weeks, but what impact does the cessation of exercise have on our brains? New research examined cerebral blood flow in healthy, physically fit older adults (ages 50-80 years) before and after a 10-day period during which they stopped all exercise.
Why do some people want to live a very long time, while others would prefer to die relatively young? In a latest study, a team of researchers investigated how long young and middle-aged adults in the United States say they want to live in relation to a number of personal characteristics. The results showed that more than one out of six people would prefer to die younger than age 80, before reaching average life expectancy.
Death and mourning were largely considered private matters in the 20th century, with the public remembrances common in previous eras replaced by intimate gatherings behind closed doors in funeral parlors and family homes. But social media is redefining how people grieve, and Twitter in particular — with its ephemeral mix of rapid-fire broadcast and personal expression — is widening the conversation around death and mourning.
The fountain of youth may reside in an embryonic stem cell gene named Nanog. In a series of experiments, the gene kicked into action dormant cellular processes that are key to preventing weak bones, clogged arteries and other telltale signs of growing old. The findings also show promise in counteracting premature aging disorders such as Hutchinson-Gilford progeria syndrome.
All cells share the same genetic code, no matter if they are skin or brain cells. However, these cells are exposed to very different types of mechanical environments and mechanical stresses. For example, brain tissue is very soft, whereas bone is hard. Researchers know that cells respond to extrinsic forces by changing their structure and their gene expression to be better suited for their particular environments and to be able to execute their specific functions.
Scientists may have overcome a major roadblock in the development of Alzheimer’s therapies by creating a new technology to observe — in the back of the eye — progression of the disease before the onset of symptoms. Clinical trials are to start in July to test the technology in humans.
A analysis of genetic mutations which cause early-onset Alzheimer’s disease suggests a new focus for research into the causes of the disease. Previous research has revolved around the idea that accumulation in the brain of a small, sticky protein fragment — amyloid beta — causes Alzheimer’s disease.
A new study is helping to explain why the long-term use of common anticholinergic drugs used to treat conditions like allergies and overactive bladder lead to an increased risk of developing dementia later in life. The findings show that long-term suppression of the neurotransmitter acetylcholine – a target for anticholinergic drugs – results in dementia-like changes in the brain.
If Parkinson’s disease wasn’t bad enough for families to have to learn to deal with, about 80% of patients also develop dementia. That’s the problem with the brain; while it has the amazing ability to adapt to just about anything, it can’t fix everything. There are no particularly good solutions to Parkinson’s or dementia, however, early detection of dementia is key to keeping it at bay and a new study may have a way to do just that.
Currently, neuroscientists think our brain has about enough storage space to hold the entire internet. That’s a lot of space, about a petabyte in fact — if we are to believe this estimate. So, what did you read in the news this day 5 years ago? Don’t worry, I don’t even remember what I had for breakfast this morning and my long-term memory doesn’t fair much better. However, vital information about how the brain erases long-term memories has been uncovered by researchers.
Alzheimer’s disease, is anything more frustrating than seeing someone — who otherwise looks healthy — start to forget who you are? Worse than that, we don’t know exactly what causes Alzheimer’s disease, or how to stop it. Well actually that might be changing. Don’t get too excited, because we’ve had false starts before, but an international group of scientists have succeeded in sorting out the mechanism of Alzheimer’s disease development and possibly distinguished its key trigger.
Taking the stairs is normally associated with keeping your body strong and healthy. But new research shows that it improves your brain’s health too — and that education also has a positive effect. Researchers found that the more flights of stairs a person climbs, and the more years of school a person completes, the “younger” their brain physically appears.
What helps her live longer might be harmful to him, according to a new study that may shed light on how and why organisms age. Analyzing years of previous research on dietary and pharmaceutical tests on flies and mice, researchers showed that aging interventions can have opposite effects on mortality rates in males versus females.
Plasticity of the brain, what does that even mean? Well the good news is that it isn’t just a marketing ploy, the brain needs to be “plastic” because we need to be able to adapt. Frankly speaking, the brain still has a lot to learn about itself. Scientists at the Virginia Tech Carilion Research Institute have made a key finding of the striking differences in how the brain’s cells can change through experience.
A team of researchers led by UNSW Australia scientists has discovered how connections between brain cells are destroyed in the early stages of Alzheimer’s disease – work that opens up a new avenue for research on possible treatments for the degenerative brain condition.
Stem cells that have been specifically developed for use as clinical therapies are fit for use in patients, an independent study of their genetic make-up suggests. The research – which focused on human embryonic stem cells – paves the way for clinical trials of cell therapies to treat conditions such as Parkinson’s disease, age-related degeneration of the eyes and spinal cord injury.
The notion that older people are happier than younger people is being challenged following a recent study led by a University of Bradford lecturer. In fact it suggests that people get more depressed from age 65 onwards. The study, led by psychology lecturer Dr Helena Chui, builds on a 15-year project observing over 2,000 older Australians living in the Adelaide area.
The same lipid that helps algae swim toward the light also appears to enable one type of brain cell to keep cerebrospinal fluid moving, researchers report.
Lack of adequate sleep can do more than just make you tired. It can short-circuit your system and interfere with a fundamental cellular process that drives physical growth, physiological adaptation and even brain activity, according to a new study. Albrecht von Arnim, a molecular biologist based in the Department of Biochemistry and Cellular and Molecular Biology, studied plants but said the concepts may well translate to humans.
Why some people live much longer than others is an enduring mystery. Now, based on a study of a worm, scientists are getting one step closer to understanding longevity. They report that the metabolic profiles of the worms could accurately predict how long they would live and that middle age could be a key turning point.
Neural stem cells generate new neurons throughout life in the mammalian brain. However, with advancing age the potential for regeneration in the brain dramatically declines. Scientists now identified a novel mechanism of how neural stem cells stay relatively free of aging-induced damage. A diffusion barrier regulates the sorting of damaged proteins during cell division.