A new study from the Gladstone Institutes shows that a single drop of blood in the brain is sufficient to activate an autoimmune response akin to multiple sclerosis (MS). This is the first demonstration that introduction of blood in the healthy brain is sufficient to cause peripheral immune cells to enter the brain, which then go on to cause brain damage.
Mitochondria are the “powerhouse of the cell.” We all learn in biology that they have seemingly one function in the body, converting food and oxygen into energy. Well that might not be the case anymore; the thousands of mitochondrial DNA (mtDNA) molecules present in each cell have been identified in an unexpected relationship with the innate immune response.
Stem cells derived from human amnion have for some time been considered promising for cell therapies because of their ease of access, ability to differentiate, and absence of ethical issues. Now, a research team has found that stem cells derived from human female amnion also have immunosuppressive activity and that the addition of antibodies to specific factors can enhance their immunosuppressive potential.
The immune system is sort of this big enigma, we know how pieces of it work, but we don’t know it as well as we would like or we wouldn’t have autoimmunity to contend with. Well new research reveals new information about how our immune system functions, shedding light on a vital process that determines how the body’s ability to fight infection develops. Which brings us one step closer to the big picture of the immune system.
How do you take out an unstoppable enemy? You don’t take the enemy head on, you take out the supply lines and the rest will take care of itself. This is not a new idea, but this not so new approach to war is being taken to an enemy on a new battlefield, your body.
Cancer in most cases can be an unstoppable force, collateral damage from chemotherapy can be, and in most cases is unacceptable. That was the thinking from a group of researchers from the Abramson Cancer Center and the Perelman School of Medicine at the University of Pennsylvania. Their idea, to attack the supply lines instead of the enemy directly.