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Archive for August 3, 2015

New approach for making vaccines for deadly diseases

Protection against dengue disease by synthetic nucleic acid antibody prophylaxis/immunotherapy

Researchers have devised an entirely new approach to vaccines – creating immunity without vaccination. The team has demonstrated that animals injected with synthetic DNA engineered to encode a specific neutralizing antibody against the dengue virus were capable of producing the exact antibodies necessary to protect against disease, without the need for standard antigen-based vaccination. Importantly, this approach, termed DMAb, was rapid, protecting animals within a week of administration.