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Pupil response predicts depression risk in kids

pupil response and depression

Findings suggest that physiological reactivity to sad stimuli, assessed using pupillometry, serves as one potential biomarker of depression risk among children of depressed mothers. Image credit goes to: Jonathan Cohen, Binghamton University Photographer

Most parents don’t want to think about their children as depressed, but that can be a deadly mistake. Short of clinical diagnosis through cost prohibitive therapy, there is no real way to tell if a child is at risk for depression. However, according to new research from Binghamton University , how much a child’s pupil dilates in response to seeing an emotional image can predict his or her risk of depression over the next two years.

The new findings suggest that physiological reactivity to sad stimuli, assessed using pupillometry, serves as one potential biomarker of depression risk among children of depressed mothers. Notably, pupillometry is an inexpensive tool that could be administered in clinical settings, such as pediatricians’ offices, to help identify which children of depressed mothers are at highest risk for developing depression themselves.

“We think this line of research could eventually lead to universal screenings in pediatricians’ offices to assess future depression risk in kids,” said Brandon Gibb.

Gibb recruited children whose mothers had a history of major depressive disorder and measured their pupil dilation as they viewed angry, happy and sad faces. Follow-up assessments occurred over the next two years, during which structured interviews were used to assess for the children’s level of depressive symptoms, as well as the onset of depressive diagnoses.

Children exhibiting relatively greater pupil dilation to sad faces experienced higher levels of depressive symptoms across the follow-up as well as a shorter time to the onset of a clinically significant depressive episode. These findings were specific to children’s pupil responses to sad faces and were not observed for children’s pupillary reactivity to angry or happy faces.

Sources:
Burkhouse, K., Siegle, G., Woody, M., Kudinova, A., & Gibb, B. (2015). Pupillary Reactivity to Sad Stimuli as a Biomarker of Depression Risk: Evidence From a Prospective Study of Children. Journal of Abnormal Psychology DOI: 10.1037/abn0000072

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One response

  1. ano

    Without paying for the article, I couldn’t tell, but is the test really suitable for screening? I mean, what is the specificity and sensitivity of this pupillometry test?

    July 7, 2015 at 1:36 pm

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