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We're a little crazy, about science!

Archive for April 2, 2015

Beta secretase inhibitors offer treatment for Alzheimer’s disease

alzhemers

With each new amyloid-targeting treatment for Alzheimer’s disease that has been developed, there has been a corresponding concern. For example, antibodies targeting amyloid-β peptide (Aβ) produce inflammation in the brain in some patients. Gamma secretase inhibitors tend to produce adverse effects by interacting with Notch, an important pathway for cellular signaling. However, a new target for alzheimer’s is offering some new hope.

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Underage drinking has lasting effects on the brain and epigenetics

underage drinking

The rise of underage drinking has almost left a sense that it is acceptable or even free of long-term consequences. Unfortunately because the brain continues forming long into the early twenties, environmental factors can have a large impact on the development. In fact, research shows that binge-drinking during adolescence may perturb brain development at a critical time and leave lasting effects on genes and behavior that persist into adulthood.

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