We're a little crazy, about science!

Archive for March, 2015

An apple a day may keep the children away: Pesticides and sperm count

DangerPesticides

Ever hear that old saying an apple a day keeps the Doctor away? Well it might have the right idea, just the wrong person. New research investigating the relationship between eating fruit and vegetables containing pesticide residues and the quality of men’s semen has shown a link with lower sperm counts and percentages of normally-formed sperm. So for people wanting children it may be time to rethink that produce.

(more…)


Ovulation changes women’s desire for variety in products

women-shopping

We know that hormones affect who we are, even when we aren’t aware of it. In the past scientists have found that people who are hungry tend to buy more things, no surprise for those of us who have shopped hungry. However, new research shows that women seek a greater variety of products and services, specifically when they are ovulating.

(more…)


Welcome to the wikipedia for neurons

brain neuroscience

While the brain might not have more connections than stars in the universe (sorry guys), it is still complex. In fact, someone I respect defined a neuroscientist as “someone who knows how little we know about the brain.” Despite the decades worth of data that has been collected about the billions of neurons in the brain, we still don’t know much. So to help scientists make sense of the vast amount of information we already collected, researchers used data mining to create neuroelectro.org, a publicly available website that acts like Wikipedia, indexing physiological information about neurons.

(more…)


UK Researchers find parental perception of child’s weight is skewed

Childhood-Obesity

Childhood obesity affects more than double the amount of children it did 30 years ago, according to the Centers for Disease Control and Prevention(CDC). To figure out why the rate is increasing researchers studied the relationship between parents and their obese children to determine how to improve pediatric health. The study actually reveals how poorly parents rate their own child’s weight issues — at least until they reach extreme levels of obesity.

(more…)


Biofuel, good for the environment if you’re eating less

ethanol gas from corn

When the government first changed policy to require ethanol in gasoline, we were told it would reduce our carbon footprint. Then food prices rose significantly and corn in particular saw the largest price rise. This was because corn is a staple in production of almost any other food from eggs to beef, but the policy made environmental sense. Well it made sense, until you found out that the new policy also took into account people eating less.

(more…)


Too much attention can be a deficit

Sometimes you need to unfocus

Sometimes you need to unfocus

Sometimes being too focused on a task is not a good thing. During tasks that require our attention, we might become so engrossed in what we are doing that we fail to notice there is a better way to get the job done. For example, let’s say you are coming out of a New York City subway one late afternoon and you want to find out which way is west. You might begin to scan street signs and then suddenly realize that you could just look for the setting sun.

(more…)


Researchers find how body’s good fat talks to the brain

The typical areas where brown fat is stored in adults. (Unknown original source)

The typical areas where brown fat is stored in adults. (Unknown original source)

There are two types of fat we humans have — white and brown — unfortunately only one of them is “good fat” and it is unfortunately not the one we tend to produce. Well new research shows that brown fat tissue, the body’s “good fat,” communicates with the brain through sensory nerves, possibly sharing information that is important for fighting human obesity, such as how much fat we have and how much fat we’ve lost.

(more…)


Research on medical abortion/miscarriage may change international routines

pro-choice-symbol

Two scientific studies are expected to form the basis of new international recommendations for the treatment of medical abortions and miscarriages. One of the studies shows that it is possible to replace the clinical follow-up examinations recommended today with medical abortions that include a home pregnancy test. The other study shows that midwives can safely and effectively treat failed abortions and miscarriages in rural districts of Uganda.

(more…)


Music played by professionals activates genes for learning and memory

music professional musician

Music performance is known to induce structural and functional changes to the human brain and enhance cognition. However, the molecular mechanisms underlying music performance have been so far unexplored. A Finnish research group has now investigated the effect of music performance (in a 2 hr concert) on the gene expression profiles of professional musicians from Tapiola Sinfonietta (a professional orchestra) and Sibelius-Academy (a music university).

(more…)


Stereotype lowers math performance in women, no one noticed

stereotypes

Stereotypes about people can affect how we look at a person, but sometimes it causes other problems. Gender stereotypes about women’s ability in mathematics negatively impact their performance. And in a significant twist, both men and women wrongly believe those stereotypes will not undermine women’s math performance — but instead motivate them to perform better.

(more…)


High-fat diet causes brain inflammation and alters behavior

high fat diet

We hear in the media all the time, obesity is effecting our health. In most cases when we talk obesity we are talking about heart disease, sedentary activity, or chronic overeating. But what if a high-fat diet — regardless of obesity — has more than just an affect on your waistline? What if the consumption of fatty foods can change your behavior and your brain?

(more…)


Immunotherapy, a promising new treatment of Alzheimer’s disease

Alzheimers_elderly

Alzheimer’s disease, it slowly takes things away from the person without giving anything back. Right now there is no cure and at best we can slow the progression in some cases. Time is always a factor and no two cases are the same. However, new treatments are in the works and a new study has revealed that a single dose of an immunotherapy reverses memory problems in an animal model of Alzheimer’s disease.

(more…)


Cracking the blood-brain barrier with magnetic nanoparticles

Blood-Brain Barrier

The blood-brain barrier, the thorn in the side of medicine. It makes using drugs directed for the brain ineffective at best and unusable at worst. This barrier runs inside almost all vessels in the brain and protects it from elements circulating in the blood that may be toxic to the brain. This barrier means that currently 98% of therapeutic molecules are also unable to cross to the brain. However, researchers now say magnetic nanoparticles can open the blood-brain barrier and deliver molecules directly to the brain.

(more…)


FDA struggles to define what “natural” means for food labels

all natural food label

After decades of debate there remains no generally accepted definition of a “natural” food product. Despite a gamut of products with the label prominently displayed, it has caused a headache in lawsuits for the government who have yet to define “natural”. According to new research, while regulatory agencies have refused to settle the issue, they may be under new pressure from those consumer lawsuits.

(more…)


Milk, not just for your bones, for your brain

cow milk

Milk, depending on who you ask it’s either great or the devil. In the US drinking milk is common; not so much in other parts of the world. This has lead to questions about why we even drink milk and how real its reported health claims actually are. Well new research has found a correlation between milk consumption and the levels of a naturally-occurring antioxidant called glutathione in the brain in older, healthy adults.

(more…)


The neurological basis for anorexia nervosa

mirror mirror anorexia

Most of us know about dieting, and if not first hand, have seen in the news or from friends how hard sticking to a diet long-term can be. This is because adults (regardless of their weight_ resolve to lose weight. Yet, more often than not, that chocolate lava cake is too enticing and that resolve vanishes. This behavior is normal because hunger increases the intensity of food rewards. Yet, individuals with anorexia nervosa (AN), despite their state of starvation, are able to ignore such food-related rewards.

(more…)


Special microbes make anti-obesity molecule in the gut

Intestine

You’ve probably heard of all sorts of diets, paleo, low-fat, low-carb, atkins, but now microbes may just be the next diet craze. Researchers have programmed bacteria to generate a molecule that, through normal metabolism, becomes a hunger-suppressing lipid (fat). Mice that drank water laced with the programmed bacteria ate less, had lower body fat and staved off diabetes — even when fed a high-fat diet — offering a potential weight-loss strategy for humans.

(more…)


Squid prolifically edit RNA to enrich their DNA

squid

DNA, it’s what makes us, well us! Not that long ago, before we sequenced human DNA we assumed we had one of the largest genomes around. Frankly it wasn’t a bad assumption, but of course we found out this was far from the case and to make ourselves feel better we said size doesn’t matter. But one of the surprising discoveries to emerge from comparative genomics is that drastically different organisms–humans, sea urchins, worms, flies –are endowed with a more or less common set of genes. So given a similar DNA blueprint, how do species develop such vast differences in physical shape, size, and complexity?

(more…)


The impact of military deployment on children

US Army's Third Infantry Divison deploys to Afghanistan for the final time

Being a military family is hard, it’s hard for the person serving (obviously) and if divorce rates are any indication, it is also hard on the spouse. While the added stress of deployment on a family cannot adequately be explained, even as someone who has seen it first hand, those stresses affect even the littlest members of the family. A new study reports that following military parents’ return from combat deployment, their children show increased visits for mental healthcare, physical injury, and child maltreatment consults, compared to children whose parents have not been deployed.

(more…)


Not “just in your head,” brain networks differ among those with severe schizophrenia

schizophrenia

The brain is plastic, it’s how we grow, it’s how we adapt, it is quite literally how we survive. This can unfortunately be to our detriment and new research shows that people with a severe form of schizophrenia have major differences in their brain networks compared to others with schizophrenia, bipolar disorder and healthy individuals. So while it may be true, that it is all be in your head, it isn’t how people usually mean it.

(more…)


Is diet soda making you fat?

Diet soda on the shelf

The diet soda controversy is still raging on, study after study has been coming in saying that it helps weight loss, it hurts weight loss, and frankly it can all be a little confusing. Well this probably won’t help matters any, a new study shows that increasing diet soda intake is directly linked to greater abdominal obesity in adults 65 years of age and older. These findings raise concerns about the safety of chronic diet soda consumption, which may increase belly fat and contribute to greater risk of metabolic syndrome and cardiovascular diseases.

(more…)


Does watching porn affect your performance in bed?

internet search page reflected in eye

Pornography, it’s why google and other search engines have safesearch. It’s all around us and if sales are any indication, it is not going away. There have been lots of claims regarding it, but does a predilection for porn mean bad news in bed? That’s the conclusion of many clinicians and the upshot of anecdotal reports claiming a man’s habit of viewing sex films can lead to problems getting or sustaining an erection, but what does science say?

(more…)


Folic acid supplementation cuts stroke risk in adults with high blood pressure

skull stroke

When we think hypertension (high blood pressure) you might not think stroke risk. However, high blood pressure can damage arteries, which often leads to an increased risk for a stroke. But if you suffer from hypertension, you might not need an expensive drug to lower your risk. A new study that included more than 20,000 adults in China with high blood pressure but without a history of stroke or heart attack, the combined use of the hypertension medication enalapril and folic acid, compared with enalapril alone, significantly reduced the risk of first stroke.

(more…)


Antibody therapy offers possible cure for psoriasis

psoriasis

Sure it’s not sexy, you probably won’t be asked for donations towards a cure, or to run/walk/dive for awareness, and it probably won’t kill you. Psoriasis is an autoimmune disease, but chances are you are not familiar with it. It causes red, scale-like patches, sometimes covering a majority of the body. It’s itchy, painful, and embarrassing (to put it nicely). I know first hand as I suffer from it albeit mildly. I say mildly since I am lucky the patches are fairly small, but not so lucky for me they pop up on my face, often. However, new research is offering hope for anyone suffering from psoriasis and possibly a cure.

(more…)


How gene expression is kept in check and the implications for cancer

DNA helix

Cancers are alive in a sense, they are similar to a parasite and they fight to stay alive when we just want them gone. Cancers have access to complex ways of avoiding elimination and because we cannot easily do anything to treat it short of surgery or chemotherapy, we regularly lose to some of the more cunning types. Now researchers have learned how living beings can keep gene expression in check — this might partly explain the uncontrolled gene expression found in many forms of cancer.

(more…)


Classical Music modulates genes responsible for brain functions

music memory alzheimer's

Although listening to music is common in all societies, the biological determinants of listening to music are largely unknown. According to a latest study, listening to classical music enhanced the activity of genes involved in dopamine secretion and transport, synaptic neurotransmission, learning and memory, and down-regulated the genes mediating neurodegeneration. Several of the up-regulated genes were known to be responsible for song learning and singing in songbirds, suggesting a common evolutionary background of sound perception across species.

(more…)


Depressed parents cause anxiety and bad behavior in toddlers

Credit for this all too true look at parenting goes to the one and only The Oatmeal, you can find more minor differences here.

Credit for this all too true look at parenting goes to the one and only The Oatmeal, you can find more minor differences here.

Being a new parent can be stressful, new mothers can suffer from postpartum depression and even new fathers can find the changes stressful enough to cause depression. Unfortunately– and if that wasn’t bad enough– a new study shows that a father’s depression during the first years of parenting – as well as a mother’s – can put their toddler at risk of developing troubling behaviors such as hitting, lying, anxiety and sadness during a critical time of development.

(more…)


Study shows modest reductions in ER visits from the ACA implementation

emergency room

It’s future might still be in the air to those of us not on the supreme court, but two patient groups created by the Affordable Care Act (or ACA, also known as “Obama care”) – Medicare patients enrolled in federally designated patient-centered medical homes and people under age 26 who are allowed to remain on their parents’ health insurance – had slightly fewer emergency department visits than they had before health care reform. However, there was no change in the rate of the most expensive types of emergency visits: those that lead to hospitalization.

(more…)


The cerebral cortex: we can rebuild it, we have the technology

brain gears

While the first actual bionic man (or woman) might still be a ways off, the writers of the show might be impressed at this. A international team of researchers, have just taken an important step in the area of cell therapy: repairing the cerebral cortex of the adult mouse using a graft of cortical neurons derived from embryonic stem cells.

(more…)


Part of the diabetes puzzle solved… with breast milk

mom baby

There is a long-standing puzzle in the diabetes field, only a small subset of insulin-producing beta cells in the pancreas of adult organisms can replicate (and hence contribute to beta cell regeneration in diabetes). Furthermore, this subset of replicating cells continues to decline with advancing age. This means that the typical risk for diabetes gets higher as you age, well now researchers have discovered an important piece of the puzzle.

(more…)


New understanding of genetics behind the autism spectrum

autism

Autism is a spectrum, because it isn’t a clear-cut diagnosis — and because the brain is so complex — it has been hard to figure out what causes autism. This uncertainty has led rise to the anti-vaccination movement along with other groups who are at best misinformed and at worst trying to make a quick dollar. However, a new study reveals an important connection between dozens of genes that may contribute to autism, a major step toward understanding how brain development goes awry in some individuals with the disorder.

(more…)


Alzheimer’s, the autoimmune disease?

alzheimers older man

Brain levels of the lipid ceramide are high in Alzheimer’s disease, and now scientists have found increased levels of an antibody to the lipid in their disease model. While some members of this lipid family are a plus in skin cream, inside the brain, ceramide appears to increase beta amyloid production and help the iconic plaque kill brain cells in Alzheimer’s.

(more…)


Trust issues? It may be your brain structure

trust

Ever feel too trusting, or maybe not trusting at all? Well a recent study shows differences in brain structure according to how trusting people are of others. Teasing out the intricacies of the brain hasn’t been an easy job; if it were we probably wouldn’t be intelligent enough to figure it out. Because of this complexity, we also have higher risk of psychological conditions. Interestingly enough, this research may have implications for future treatments of those conditions, conditions such as autism or other attachment disorders.

(more…)


New approach to herpes vaccine succeeds where others failed

HSV

Herpes simplex virus infections are an enormous global health problem and there is currently no viable vaccine. For nearly three decades, immunologists’ efforts to develop a herpes vaccine have centered on exploiting a single protein found on the virus’s outer surface that is known to elicit robust production of antibodies. Breaking from this approach, Howard Hughes Medical Institute (HHMI) scientists at Albert Einstein College of Medicine have created a genetic mutant lacking that protein. The result is a powerfully effective vaccine against herpes viruses.

(more…)


People with anorexia and body dysmorphic disorder have similar brain abnormalities

Adonis-complex

Imagine looking in the mirror and not seeing yourself. Imagine losing weight and seeing a lower number on the scale, but when looking in the mirror you are still just as fat. Suffering from anorexia or other body dysmorphic disorders live like that daily. They literally don’t see what you and I might see when we look at them. It’s not their fault and a new study suggests that people suffering from anorexia or body dysmorphic disorder have similar abnormalities in their brains that affect their ability to process visual information.

(more…)


Not “just” crazy – Some psychoses caused by autoimmunity

schitzophrena

Antibodies defend the body against bacterial, viral, and other invaders. But sometimes the body makes antibodies that attack healthy cells. In these cases, autoimmune disorders develop. Immune abnormalities in patients with psychosis have been recognized for over a century, but it has been only relatively recently that scientists have identified specific immune mechanisms that seem to directly produce symptoms of psychosis, including hallucinations and delusions. In other words, some forms of psychoses might just be an autoimmune disorder.

(more…)


Team accidentally finds key to DNA vaccination and genetic engineering

genetic engineering

It might have been an accident, but for some lucky researchers accidents are a good thing. In this particular case, scientists have discovered a new way to manipulate how cells function, a finding that might help advance an experimental approach to improving public health: DNA vaccines, which could be more efficient, less expensive and easier to store than traditional vaccines.

(more…)


A study of twins shows that autism is largely genetic

autism camp

In the fight against misinformation about autism it seems science is starting to come out on top, finally. A new study hopes to add to the recent advancements made in the understanding of autism, which finds that a substantial genetic and moderate environmental influences were associated with risk of autism spectrum disorder (ASD) and broader autism traits in a study of twins.

(more…)


Who’s Leonard Nimoy?

Star trek

“I’m having a crappy day and to top it off Leonard Nimoy died today.” I told my friends as I was getting into the car after a particularly challenging day. No, I was not a huge trekkie growing up, but I did have a lot of respect for Leonard Nimoy and for Spock, the character that seemingly only he could bring to life. Truthfully, Spock and I had a lot in common, we were both mixed and neither one of us had an easier time for it. I typically don’t share my personal story here at the Labs, but I thought I would make an acception.

(more…)


Early life stress may result in a serotonin deficiency

my_suicidal_secret_by_howcouldyoudothat

If you have experienced — or are experiencing — mood disorders like anxiety or depression, you know about SSRI’s and chances are they didn’t do much for you. In fact studies indicate that the majority of people with mood and anxiety disorders who receive Selective Serotonin Reuptake Inhibitors (SSRI’s) are not helped by these medications. Sadly, they are the most commonly prescribed class of antidepressant medications, this is because SSRIs are designed to increase serotonin levels, a neurotransmitter in the brain that is key to maintenance of mood.

(more…)


Drug already on the market could help treat MS and other neurological diseases

multiple_sclerosis

Multiple sclerosis, unless you suffer from nerve damage it is a pain you (thankfully) will never have to feel. In most cases, treating the brutal pain caused by this (and other neurological diseases) is the only help that can be offered to people. The pain is caused by damage to myelin, the fatty insulator that enables communication between nerve cells, which characterizes multiple sclerosis (MS) and other devastating neurological diseases.

(more…)


Science shows intermittent fasting diet could extend life

sandwich

Think of it as interval training for the dinner table. Proponents of fasting style diets will be first to tell you there are health benefits, heck we’ve even covered some of the science here at the labs. Well new research shows that putting people on a intermittent fasting (or IF) diet may mimic some of the benefits of  actual fasting, and that (ironically enough given their popularity) adding antioxidant supplements counteracts those benefits.

(more…)