More on experimental prep
Since we have a rather large and cumbersome set of experiments happening it’s my job to make sure they go off without too much trouble. I say too much trouble because no matter how much you plan, test, and retest, something will go wrong. Heck it may not even be wrong on our end, it may be wrong on someone else’s side, but that’s why we plan. So once again I’m talking about how we prep for our experiments.
(more…)Adventures in experimental design
When did people start trusting me with experimental design? I have no idea, but here we are and I’m helping come up with a series of experiments we will be doing in roughly one week… seven days. So between now and then, we have a lot of things to figure out. We have a rough idea about what will happen, but there are a lot of moving parts and it turns out we are probably missing a few things so we’re going to have to get creative if we really want to get to the bottom of things… fun times for all!
(more…)Whatever it takes
Well, yesterday happened. If you’ve been following around for awhile the last time I didn’t write a post we were dealing with apocalyptic weather (as in no power bad). So I think after years of being consistent, I wouldn’t blame you if you thought something bad had happened. In reality, there was just a mountain of work and no time to relax. I don’t like pushing myself like I had to yesterday, but it was for a good cause or at least I think so, or I wouldn’t have done it.
(more…)The mysterious data
I sometimes miss the days when the answers were in the back of the book. At this point I would take even just having answers that are semi related to the questions I’m trying to work out. Being a researcher is a double edged sword. On one side, for a brief moment in history you will know something that no other person in the world knows. On the other, how do you know that it’s correct? Questioning your results is an important part of research and right now, there’s more questions than answers.
(more…)Mounting pressure
After yesterday’s win, you would think things would be smooth sailing, but alas that isn’t in the cards! I mean yesterday’s good news still applies thankfully, but wow did I wake up to a flurry of emails and now a mountain of work that all needs to be addressed all at the same time. Wait, is there an echo in here? I feel like we’ve done this before…
(more…)A big result
I’m stepping away from my planned sharing of the notes from my lecture to bring breaking news! For those who don’t understand what’s going on, a while ago I had an idea, a “big idea” that I’m convinced will be the thing I’m known for… if it works. And our first attempt was not great. In fact, we got absolutely nothing. The second and third attempts however we were ready and it looked like we had something. The question is what did we have?
(more…)From imagination to reality
It’s amazing what a good night of sleep will do for a person. Hopital-PI often has what he calls his “shower ideas” and frankly, my “big idea” was also a shower idea, but I find that the best ideas come to me when you’re not even thinking about them. When you step away from a problem and focus on something else, your brain just does something magical and works out the solution without you even realizing it, sometimes anyway.
(more…)A dissertation dilemma
Okay, since I’m still waiting on my new and fancy toys to arrive for my dissertation I’ve been debating about going through the whole thing once again using the equipment I already have access to. Since there’s a limited amount of time I may just have to power through and go ahead with data collection using the old equipment, but it’s still anyone’s guess if I’ll do that because frankly I’m not sure it will be worth it. Since it’s up in the air, I figure I can write out my thought process and hopefully figure it out one way or the other.
(more…)Semi-final paper edits
Okay, with all the “big” things happening the past few days I really need to switch gears and focus on the other major deadline I’ve got coming up and that’s the response to “last paper,” which is still not due for another 2-3 weeks I believe so I still have time, but it’s not just me that needs to sign off on it, it’s all my collaborators and that is the problem. Mostly because last paper took so long in part due to disagreements within our group.
(more…)The big payoff
Yesterday I finally had the chance to get not one, but two new datasets! Those datasets were for a project I’m calling “big idea.” In my mind, it will change the way a lot of things are done, advance science, and I even joked with hospital-PI that I would need to retire after we publish because I’ll never do anything better. I have a lot of hope for big idea, but the first dataset we got was a fail, so the question was, what happened and did we fix it?
(more…)The big data haul
It’s been one hell of a week and it’s only Monday. Experiment days are always hard, but when you’re doing multiple experiments in one day in, let’s say not so ideal situations, it can be hard. But we’ve made it out the other side! Unfortunately, just because the experiment is over, doesn’t mean things get any easier. At least in this case, because now comes the hard part.
(more…)Another big experiment!
Things have been off to a rocky start for my “big idea” there’s a lot of moving parts, people to coordinate with, and things to manage. It’s no surprise things haven’t gone well since we started trying to get this project off the ground, but we’re still trying and that has to count for something… right? As it turns out, we may have lucked out this next week!
(more…)New equipment
Things are looking up! After last weeks attempt at collecting data for my PhD, I realized how important it would be for the new equipment I requested to be ordered and in my hands the next time I’m collecting data. Unfortunately there’s a process to getting new equipment and despite having funding for my project, there is no direct way to spend the money. Instead there is a winding path you need to follow in order to get equipment in a research lab.
(more…)The next big experiment
Well things are moving fast around here, like I predicted they would this year. Of course, things are currently going better than I had hoped, but that could change. Last week was a busy one and next week will be no different, but next week is a particularly big week, because I’m going to be doing another experiment for a somewhat different project. Yep, another “big idea” experiment is coming.
(more…)Experiment prep
Tomorrow is my first experiment! To get ready I have a few loose ends to tie up before the big day. Mostly I just need to write everything out, make a list of items I need to set up, organize a few things, the stuff no one thinks about when they head off to an experiment. Tomorrow is going to be bumpy, but the first time always is, so best to be prepared.
(more…)The first dissertation experiment
It had to happen eventually! But not today, this Friday however will mark the first of several experiments I will be undertaking in the (currently) slow march to my PhD. In an effort to help people understand that experiments aren’t just something that happens at the scheduled time, let’s take a look behind the scenes at what I need to do between now and Friday to get ready. It’s going to be a looong week.
(more…)The mental health stigma
You don’t look depressed. Chances are if you struggle with depression you’ve heard that once or twice, or dozens of times on a seemingly never ending loop. If you have a broken bone you can be diagnosed via an x-ray or CT. If you have cancer, there are blood tests or MRI scans that can catch it. If you get sick, rapid tests or PCR will tell you if it’s COVID. But how do you diagnose depression?
(more…)The lab brain drain
Today was another proposal defense! No, not mine thankfully, but one of my labmates who’s been in the lab for some time now. As the term is coming to a close, I think a lot of us are in the proposal defense phase, which means things will be changing dramatically in a year or so for the lab. It made me realize that there was a rather large gap between those of us finishing and the new members, which means big changes once we graduate.
(more…)The cost of research
I’m not sure why, but lately I’ve been tasked with gathering quotes for new equipment. It’s not even just with the hospital side of things either, the school side has suddenly asked me for quotes as well. I understand the logic of having gather the quotes like this, after all it’s a huge time sink, but I’ve learned a lot over the past month or so from dealing with all this and that is research isn’t cheap.
(more…)The return of last paper
If you love something set it free, if it comes back it was meant to be. What a bunch of garbage. Well maybe just in this case. I’ve slowly gotten out from under the weight of not one, but four different first author journal papers I’ve been working on. Three of the four are published (with one going live any day now… I think?! That should’ve happened a week ago…), but one paper, last paper, has been a struggle all its own and now it’s back with a vengeance.
(more…)3 aims, 2 experiments, 1 year
It’s now official, I have a rough timeline for everything I want to do and I’ve got the greenlight from my committee that the work I propose to do will be enough to earn my PhD. I’ve spent the past day trying to plan out the rough outline of what the next year will look like in context with all the other work I will be doing and it will be busy!
(more…)The last project
Today was my proposal defense day and I would like to say it went well. I would like to. Kidding, I think things went okay. I’ll leave that to the handful of people who read my blog regularly to judge. My committee members all thought the work was interesting and my plan of attack was good, so now the real work begins. It’s the last project before I get my PhD.
(more…)The main event
Well tomorrow is D-day, proposal defense day that is. Technically there will be one more defense day after that, my actual PhD defense. The difference being, when that’s all done I’ll have a piece of paper to show for my efforts. That won’t come until next year… hopefully. But in the meantime, tomorrow is the (other) big day and I’m getting just a touch nervous! After all, it’s only the next year or so of my life I’m laying out for my committee members, what could go wrong?
(more…)An ounce of preparation
What a week. It’s only Wednesday and it feels like it’s just never going to end. There are three major events coming up this week, meaning I will be working this weekend unfortunately, but at least I made it through the day. Tomorrow will be a major event for me, dare I say bigger than my proposal defense just two days away.
(more…)The return of big idea
I had hoped to discuss robot paper today, but something more exciting has happened so today we’re talking about the “big idea’ I had a while back. It feels like it’s been forever since I had the idea, but things were moving slowly lately so we’ve had to wait. I’m happy to say the wait is finally over! If all goes well, by the end of the week I’ll have the first dataset from big idea and I am very excited!
(more…)The proposal defense date
Okay not going to lie I had a minor freakout the past few days. One of my committee members wasn’t responding to my emails so I could not schedule my proposal defense. Last night out of the blue, reality smacked me in the face and it occurred to me that next week was the first week I was trying to schedule and time was running out. People are busy and I didn’t want any of the PI’s to have a conflict. But it all worked out…
(more…)New and old projects
It’s finally my chance to put my own spin on the stuff coming out of the hospital lab and I’m incredibly excited about what is coming. Unfortunately I can’t talk about it! However, I’m hopeful that this year will be an excellent year for me with regards to the research I’m doing. Things are slowly falling into place and while we’re still at the beginning, things are looking bright.
(more…)The big rush
A while ago I had an idea, a “big idea,” but the second I had that idea the clock was ticking. Because ideas are not that unique. There is a gap in research and we try to fill that gap when we see it. I noticed a gap and because I noticed it, there’s no reason others won’t notice it as well. Now we’re in an unseen race to publish and there’s still some speed bumps in the way that are causing some issues. I’m hopeful we can get there first, but I wouldn’t be surprised if we had competition.
(more…)The other presentation
With just a few days to work on the project, I was asked to present the data we’ve recently finished collecting at work. The presentation will happen Monday, as in three days away Monday. So between now and then, I need to process the data, make some figures (so many figures), and generally draw some sort of conclusions based on the work.
(more…)The finalized proposal
Well today was kind of a big step, I’ve finalized my proposal, got school-PI’s approval to send it out, and now I’m just waiting for a few people to select their availability so we can schedule the actual defense. I’m just a touch nervous! I still need to modify my slides and of course practice, but we’re now roughly two weeks away from the actual proposal defense!!!
(more…)Committing to the story
For the past few days I’ve been talking about telling a story with your data. Because at the end of the day as a researcher that’s what we do. We do an experiment and, assuming it goes well, we have a story to tell about the result we found and what it means to the people reading the paper. Ideally any good story will have great visuals to add to the story and to help the reader. Which is where I’m still stuck…
(more…)Characterization of interlimb interaction via transcutaneous spinal stimulation
I was debating about talking about this because I’m “only” the second author on the paper. Apparently I’ve gotten picky now that I have a handful of first author papers in review/published. I’m joking, but seriously, this paper has a special place in my heart and today I want to talk a bit about the science, but also the story behind the paper, because it is an interesting one!
(more…)On the shoulders of giants
Tomorrow I’m doing something for the first time, ever. I got an email yesterday with the good news and while we don’t have all the equipment we need for the project, we can still get some good data and an early look at what the data will look like. I’m so excited I’m shaking, I barely slept last night, and my mind is swimming with the possibilities. This is what it’s like doing research on the edge.
(more…)Big claims and big evidence
In science, ideally, when you make a large claim, you need a lot of evidence to support it. In theory anyway, in practice with the speed of the internet, claims often get taken as truth no matter how self correcting later. The claim that vaccines cause autism for example has been thoroughly debunked over and over, but the claim still persists despite the piles of evidence to the contrary. Global warming is another good example of how having a lot of evidence doesn’t mean acceptance.
(more…)The value of clean data
In my line of research we have fancy algorithms to remove outside contamination to the data we collect. The problem with collecting electrophysiological data (electrical recordings from a person) is there is so much damned noise everywhere. The problem is magnified when you collect data that have a low signal to noise ratio (meaning lots of noise, not a lot of signal). Signal in this case is the thing we’re interested in measuring and while we have dozens of algorithms to filter (remove) the noise, there’s still no substitute for data that was well collected.
(more…)The first one
Ever look up an answer in the back of the book? The problem with research is there’s no back of the book, but typically when you do an experiment you can at least glance at research surrounding your work and make sure you’re not going completely off the rails. Because I like to make my life unbelievably difficult, and because I don’t like taking small steps forward, I’m going to (hopefully) be the first to do a few things this year. But it’s not as glamorous as it sounds.
(more…)And then DARPA appeared…
DARPA and I go way back. Right after I got out of the military back to be exact. Not that more than one or two people even know my name (and probably only vaguely), but DARPA is the reason I’m where I am today, even if the people who helped me get here don’t remember me. As much as I love the DARPA origin story, that’s all it’s ever been, that is until today, when school-PI let me know that DARPA was paying attention.
(more…)The IRB and committee and dissertation proposal, oh my!
Well today has been eventful! After a bunch of emails, meetings, and miscellaneous things, I have a clear shot to my dissertation proposal! I don’t want to say it’s been smooth sailing or that things won’t be rough, but I’m feeling optimistic after all the news. Since there’s a lot, I figure we can cram it into a single post as I take the next few steps to the big proposal defense day.
(more…)The PhD dissertation proposal
Well we’ve finally arrived, for real this time, to my proposal timeframe. There are a lot of things that need to happen between now and when I defend my proposal, but thankfully most of those things are started or almost finished. The one thing that isn’t started… well that would be my actual proposal. Be not afraid! I’m going to have the draft done today, or at least that’s what I’m telling myself.
(more…)A (not so) small celebration of… me
I can write small novels on the accomplishments of others and praise the work they do, because the work they do is worth praise. I think I come off overly flattering, but I mean every word of it because people deserve to be celebrated. Well sadly, I lack that ability for myself, but I’m pushing through the skin crawling feeling that I should delete this and write something else to celebrate a victory, or at least an acknowledgement of a win. So today we’re talking about my least favorite subject, me.
(more…)Back in the OR!
Well we finally got approval to head back to the OR. We were having some issues with our sample size, as in we hit the max for our protocol, but after a little bit of work we’re going back! The good news is that this doesn’t just affect the project I’m working on, this means I can move forward with the other project I’ve been dying to start.
(more…)The final push of “last paper”
Amid all the chaos that the lab visitor we had yesterday caused I wouldn’t blame the causal reader if you thought that the robot project was my only focus. Hospital-PI summed it up best when he said we’re all working on roughly four projects at any given time and I responded with, “you guys are only working on four?” Don’t get me wrong, I like it this way.
(more…)Robot troubles…
Sixty or so hours later and I somehow finished the robot assembly. It’s been a week and a half of 12 or more hour days to get it done and I’m exhausted. Still nothing feels better than when you finish, flip the switch and everything goes exactly how you hoped. Unfortunately I’m not quite at that stage… maybe?
(more…)Inter-lab rivalry
There’s nothing wrong with a little competition. In the field of research you’re either the first or your a footnote, so we rush to be the first when we know that other labs are on the other labs are not far behind. Our lab knew it was coming, there was already rumblings of something big coming from another lab, but when it finally came, we were both surprised, but not exactly shocked. It’s a pretty impressive paper.
(more…)Return of the “technique”
With all the excitement around here with the progress made towards making “big idea” a reality, you may think that I’ve forgotten about other projects and things I’m working on. That isn’t the case and I have other exciting updates regarding something I’ve been calling my “super secret technique” not the most descriptive name, but that’s sort of the point. It’s not “big idea,” but is sure isn’t a tiny idea either.
(more…)The big pitch
Today was the day we pitched a proposal to two of the doctors that can help make my “big idea” a reality. It did not go anything like I planned, some of what happened was funny, some of it was horrific, but mostly it went how it needed to go. Things never go as you plan them, but this was just completely off the rails.
(more…)A big meeting
Well I’m excited, tired but excited. It’s been a long week and that is partly because I have a meeting tomorrow to discuss a project that will be a big help in my PhD, but also a really cool project in general. We also have a second big meeting next week with some guests coming to see the research side of the hospital, so yeah busy!
(more…)In defense of pain management
Well this seems to be coming up a lot lately. One of the things about working in a hospital is you get to see a lot of different opinions and cases from doctors from all areas of expertise. It gives everyone a well rounded education and frankly no matter where you are in your career it’s always good to keep up with the state of the art in your field and adjacent fields. I’m in the neurosurgery department so we get to talk a lot about the brain and spinal cord, which means pain is a frequent topic.
(more…)The last paper
Kind of a misnomer since this is definitely not THE last paper, but it’s paper four of four. The fourth paper in my roadblock of papers where things were coming in, but for whatever reason nothing was moving forward. Now with two of the four published and one in review again after a request for edits, I’m assuming it will be accepted (sooooon!). That leaves me with exactly one paper left and there are finally updates.
(more…)Old student, new tricks
With a little luck, I’m a year away from graduating. It’s been one hell of a journey and I really hope I hit this goal. Still, I keep thinking what’s next and the truth is the future looks a lot like the present. It’s not just because I’m now working at a research hospital, that helps, but what I mean is that the difference between being a student and being a researcher isn’t all that different. You have to learn new skills.
(more…)
Lunatic Laboratories 