The next big experiment
Well things are moving fast around here, like I predicted they would this year. Of course, things are currently going better than I had hoped, but that could change. Last week was a busy one and next week will be no different, but next week is a particularly big week, because I’m going to be doing another experiment for a somewhat different project. Yep, another “big idea” experiment is coming.
(more…)The last paper response
Well it’s been a few weeks since I got the response back for “last paper” since I have roughly three weeks left to finalize all the edits they requested, this weekend I plan on tackling most/all of it so that we can get the ball rolling with my collaborators so I can (hopefully) get the response back to the editors before the deadline they set. Because there is a deadline and I do not want to be late, mostly because it will make more work for me if I am.
(more…)When DARPA calls
Fifteen years. It’s been roughly fifteen years since I started this journey and the dream was always the same. We all have stupid dreams as a kid, we want to be astronauts and sports stars, but the odds aren’t in our favor. We’re told to be realistic. Sorry kid, your dreams are too big. You need to shrink yourself to fit into the tiny box we as a society provide you. I was never good at following instructions, so maybe that’s why the past fifteen years have been a special kind of hell, but today, today made it all worth it.
(more…)The return of last paper
If you love something set it free, if it comes back it was meant to be. What a bunch of garbage. Well maybe just in this case. I’ve slowly gotten out from under the weight of not one, but four different first author journal papers I’ve been working on. Three of the four are published (with one going live any day now… I think?! That should’ve happened a week ago…), but one paper, last paper, has been a struggle all its own and now it’s back with a vengeance.
(more…)An ounce of preparation
What a week. It’s only Wednesday and it feels like it’s just never going to end. There are three major events coming up this week, meaning I will be working this weekend unfortunately, but at least I made it through the day. Tomorrow will be a major event for me, dare I say bigger than my proposal defense just two days away.
(more…)The return of big idea
I had hoped to discuss robot paper today, but something more exciting has happened so today we’re talking about the “big idea’ I had a while back. It feels like it’s been forever since I had the idea, but things were moving slowly lately so we’ve had to wait. I’m happy to say the wait is finally over! If all goes well, by the end of the week I’ll have the first dataset from big idea and I am very excited!
(more…)New and old projects
It’s finally my chance to put my own spin on the stuff coming out of the hospital lab and I’m incredibly excited about what is coming. Unfortunately I can’t talk about it! However, I’m hopeful that this year will be an excellent year for me with regards to the research I’m doing. Things are slowly falling into place and while we’re still at the beginning, things are looking bright.
(more…)The big rush
A while ago I had an idea, a “big idea,” but the second I had that idea the clock was ticking. Because ideas are not that unique. There is a gap in research and we try to fill that gap when we see it. I noticed a gap and because I noticed it, there’s no reason others won’t notice it as well. Now we’re in an unseen race to publish and there’s still some speed bumps in the way that are causing some issues. I’m hopeful we can get there first, but I wouldn’t be surprised if we had competition.
(more…)On the shoulders of giants
Tomorrow I’m doing something for the first time, ever. I got an email yesterday with the good news and while we don’t have all the equipment we need for the project, we can still get some good data and an early look at what the data will look like. I’m so excited I’m shaking, I barely slept last night, and my mind is swimming with the possibilities. This is what it’s like doing research on the edge.
(more…)The first one
Ever look up an answer in the back of the book? The problem with research is there’s no back of the book, but typically when you do an experiment you can at least glance at research surrounding your work and make sure you’re not going completely off the rails. Because I like to make my life unbelievably difficult, and because I don’t like taking small steps forward, I’m going to (hopefully) be the first to do a few things this year. But it’s not as glamorous as it sounds.
(more…)And then DARPA appeared…
DARPA and I go way back. Right after I got out of the military back to be exact. Not that more than one or two people even know my name (and probably only vaguely), but DARPA is the reason I’m where I am today, even if the people who helped me get here don’t remember me. As much as I love the DARPA origin story, that’s all it’s ever been, that is until today, when school-PI let me know that DARPA was paying attention.
(more…)The PhD dissertation proposal
Well we’ve finally arrived, for real this time, to my proposal timeframe. There are a lot of things that need to happen between now and when I defend my proposal, but thankfully most of those things are started or almost finished. The one thing that isn’t started… well that would be my actual proposal. Be not afraid! I’m going to have the draft done today, or at least that’s what I’m telling myself.
(more…)The final days of the “last paper”
Well I don’t want to get my hopes up, but I have some big news! As promised in the last, last paper update, I wasn’t going to talk about it until we had submitted the paper for review. Well as of today, last paper is FINALLY in review! Now this could be months before we get it actually published and maybe even longer if there is several rounds to the edits, but this is a big step.
(more…)The final push of “last paper”
Amid all the chaos that the lab visitor we had yesterday caused I wouldn’t blame the causal reader if you thought that the robot project was my only focus. Hospital-PI summed it up best when he said we’re all working on roughly four projects at any given time and I responded with, “you guys are only working on four?” Don’t get me wrong, I like it this way.
(more…)Return of the “technique”
With all the excitement around here with the progress made towards making “big idea” a reality, you may think that I’ve forgotten about other projects and things I’m working on. That isn’t the case and I have other exciting updates regarding something I’ve been calling my “super secret technique” not the most descriptive name, but that’s sort of the point. It’s not “big idea,” but is sure isn’t a tiny idea either.
(more…)The big pitch
Today was the day we pitched a proposal to two of the doctors that can help make my “big idea” a reality. It did not go anything like I planned, some of what happened was funny, some of it was horrific, but mostly it went how it needed to go. Things never go as you plan them, but this was just completely off the rails.
(more…)A big meeting
Well I’m excited, tired but excited. It’s been a long week and that is partly because I have a meeting tomorrow to discuss a project that will be a big help in my PhD, but also a really cool project in general. We also have a second big meeting next week with some guests coming to see the research side of the hospital, so yeah busy!
(more…)The last paper updates
Well things are moving fast. So fast I haven’t had a break. Since I have a free moment, and I really do mean moment, we might as well go for the low hanging fruit and update on the “last” paper. This paper has been in the works for years (literally years) now and we’re finally coming to a close in the chapter. At least that’s how it appears. There’s still some rough sailing ahead, but I think we’ve finally made it…. maybe.
(more…)The last paper
Kind of a misnomer since this is definitely not THE last paper, but it’s paper four of four. The fourth paper in my roadblock of papers where things were coming in, but for whatever reason nothing was moving forward. Now with two of the four published and one in review again after a request for edits, I’m assuming it will be accepted (sooooon!). That leaves me with exactly one paper left and there are finally updates.
(more…)The robot resubmission
Sometimes life comes at you fast, other times you’re writing a paper and four years later you’re still looking to publish it. Publishing can be like that and while I’m not the only one with this type of story, I do believe we’re finally coming to an end of the robot paper saga. I’m really hoping I don’t have a whole ass PhD before this thing gets published, that would just be awkward.
(more…)Robot rush
Well we’re just a few days away from robot paper deadline and there’s still some work to be done! While robot-PI is still editing the paper, I had an unfortunate realization with some of the work I had done that requires me to go in and fix a few things. So once again, I’m doing things as hard as possible.
(more…)The week ahead
Every once and awhile I like to highlight what kind of stuff I’m working on during the week and since there are a lot of things going on and none of them would make a very “full” post on their own, I think it would be best to group it all together and look ahead because there are some very interesting things happening this week!
(more…)The robot paper response
Yesterday due partly to the house work I was having done, I got none of the data processed I needed to do, but I had a chance to address some of the comments I got from the reviewers on “robot paper.” The response is due in just a few days and one reviewer was very thorough with their feedback, so there’s a lot to address and not a lot of time to get it done. The good news is ~94% of the comments are addressed, the only bad news is that it isn’t 100%.
(more…)The IRB response
That was fast. I wasn’t expecting to hear anything back from the IRB so quickly, but here we are and I have a bit of work to do. Technically we didn’t get the IRB reviewed yet, it’s only been “pre-reviewed,” but pre-review helps speed things up when the IRB meet next (in about a month) to look over the application. Since we were asked to make some modifications, this should help bring our IRB application up to standard before the IRB actually review it.
(more…)Back to back OR experiments
I’ve had one other instance where we had two OR experiments in a single day and that was exhausting. Thankfully we had a break in the middle so that I could get everything cleaned and prepped for the next time. Unfortunately I’ve just been made aware that next week we get to try things on hard mode next week.
(more…)Back in the OR
Oh man, I haven’t been in the OR since last year! Okay we’re only a few days into the new year, but it does feel like it’s been a bit with the holidays. That’s going to change though because tomorrow is our first OR experiment of the year. And with the new year, we have some new changes to the experiment that we’ll be trying since we’ve had over a half dozen attempts to do this right with somewhat mixed success.
(more…)Another new project!
In the spirit of making things as hard as I possibly can for myself I’ve gotten a new project to work on from hospital-PI. This was a known thing, but it does (mildly) clash with the idea I recently had. Since I cannot share the idea I had, we can instead talk about this project a bit and why the two will be at odds. I also have a fun update on the big idea project I came up with so I’m shoehorning it in with this post since it’s semi-related.
(more…)Return of the robot paper
Logically I knew I would get a response sooner or later, I mean you submit something to a journal and you’re going to get a response. Even if it’s just a screw you, you hack. Can you tell I’ve already had several of those? Well yesterday I finally got the email about the paper I wrote on the work I did in my Masters degree days, which feels like a very long time ago now that I’m almost done with my PhD. The news is good, but I’m going to be cautious.
(more…)Real-time seizure state tracking
Since I shared one of the papers I was super proud of, I figure I can share the other one as well. Like the last paper (here) I’ll explain the concept and why this paper was important. I’ll also talk about why I think it was cool and where the idea came from. Mostly this post is for people who are interested in the work, but may not be familiar with the technical aspects so I’ll try to avoid technical terms or I will provide an explanation when needed.
(more…)The first steps to my proposal
I said this year was going to be a ride and I meant it. We’re four days into the new year and I’ve just heard back from school-PI that I’m good to submit my IRB. Since that may sound like gibberish to the non-academic and because I like to make things accessible, today I’ll explain what an IRB is, why it’s important, and why having one is somewhere between a small step and a giant leap to my PhD.
(more…)Another OR experiment
Time to dust off my scrubs, it’s back to work for me. In fact, I have been so busy with other things I don’t think I mentioned it, but today is yet another OR experiment. With how well the previous two went, I’m hopeful that this one will go well, but a somewhat alarming email from hospital-PI yesterday may throw a wrench into any plans I had.
(more…)OR experiments, the aftermath
The good news is we have data! Lots of data, more data than you could shake a stick at, although I don’t know why you would shake a stick at anything… That’s beside the point(ed stick) though! Yesterday was not one, but two OR experiments and I have to say surgeon-PI must be in way better shape than he appears because both hospital-PI and I are exhausted!
(more…)Interrogation of spinal networks during movement preparation using transcutaneous spinal stimulation
That’s not the name of the paper, but that’s the general idea. We tend to take movement for granted, I mean most of the time we do it without thinking. I don’t look down as I’m typing these words, yet my fingers know what to do to make it happen. Similarly, we don’t really think about balancing ourselves when we walk, we just do it. So if I’m not consciously thinking about every step I take when I walk down the street, who, or what is keeping me going?
(more…)The path moving forward
Pick your battles. After having a conversation with another student about their PhD plans and how soon they want to graduate, they offered that sometimes you need to pick your battles. I couldn’t agree more with that statement and when I met with school-PI a few days ago virtually to go over my big PhD plans I asked what I needed to do to finish. I needed to pick my battles.
(more…)Double OR experiments!
It’s official, I just got not one, but two new participants for our study. This will be happening next week and the scary part is they are both on the same day, so it will be more than a full day in the OR, like 12 hours or so for the whole day. Not all of that time will be spent in the OR, thankfully. Every attempt we’ve had thus far in the OR has gotten better and better, so if the pattern holds, we should have some very good data after this next round of participants and I will have more data than I know what to do with.
(more…)Success! Journal paper 2 of 4
Well kids, Christmas has come early! As of this morning my second of four journal papers I’ve written has been accepted for publication! Since it’s been a somewhat long and confusing road, I figure today I can remind everyone why I’m so thrilled about this paper and why this is good news for me in particular. There’s still a lot to do and more papers to publish as we go, but things are looking up!
(more…)The fifth OR experiment
Well we did it. I finally have the first (mostly) complete dataset from a patient. Overall I think it went well and we got good data. Mistakes were made! But thankfully none of them derailed the project and overall I am happy with the outcome. Let’s get into what went wrong and what went right, because having some post surgical notes will help me next time we do our thing.
(more…)Prepping for the experiment
Today’s the day, experiment number five. With lot of luck this will be the first full experiment we do for this protocol. It will hopefully mark a turning point for us since after four attempts we’ve yet to get a full dataset. However, I’m hopeful, but I’m also going in alone today.
(more…)Solo OR experiment
Tomorrow will mark attempt number six to get the data we’re after from the OR. We’ve got a very unwieldy experiment to do which involves coordinating with the surgeon, but also the staff to make sure we don’t run into each other. It’s a delicate dance and if you haven’t been following along, it hasn’t been great so far.
(more…)A not so certain future
I have a lot of health problems. If I were to dedicate a post to each we would be here awhile. They affect me in ways that I’m very aware of and sometimes I’m left to wonder if they affect me in ways I don’t always notice. Maybe my communication skills are just that awful or somehow my brain just can’t make sense of things. I feel like I’m going crazy, but it has to be me… right?
(more…)A big idea…
You ever have an idea that you just KNEW would change the way you were doing things. Like the first person to invent a surgical robot, it was just a good idea and it completely changed the way things were done. I don’t think that this idea is going to change things that dramatically, but much like my super secret technique, I think my recent revelation is going to mean some great things for me. Lighting struck the other day and it has hospital-PI incredibly excited.
(more…)Journal Paper three update!
Well that was fast, we got reviews back on a paper we recently submitted and they were surprisingly good for us. It’s still considered major revisions, but they gave us ten days to make the changes. Ten days as of Monday, so were about a week away from needing to resubmit. There’s some work to be done for sure, but I think we can manage.
(more…)Fun with collaborators!
So much has been going on that I can’t even keep up with it. I was debating about what news to share, but I think we’ll talk about something I’ve had in the works for awhile now. Actually I just checked my email exchanges, this has been in the works for over a year and today we finally crossed the threshold from hypothetical to real world data collection!
(more…)Update from the OR
No, I’m not updating this while I’m in the OR, but we had OR attempt number five as a maybe today and I have good news. We managed to get a yes at the last minute and got some interesting data. It’s all very exciting, so now I need to dig around and see what we found. For sake of remembering, let’s run through how today went!
(more…)The last experiment
Goodbyes are hard, even if you don’t really know someone outside of work. Today we’re saying goodbye to a few of our participants as they finish one of our longer experiments. It feels like only yesterday, but it’s been several months now so it’s time to wrap things up. The good news is this will create a bit of an opening in my routine, but that’s probably going to be filled in pretty quickly.
(more…)Mad dash to the OR
Today has been a day! The trick with doing research in the OR is that the schedule for the surgeries don’t get finalized until the day before and sometimes even then things change at the last minute. I’m not sure when the schedule was finalized or if anything changed, but this morning I got a text that threw everything out of order. The best laid plans of mice and men…
(more…)The fourth OR experiment
It’s official! We have experiment number four coming in two days. I’m excited about another attempt to collect data and to answer about a dozen interesting questions since we just keep tacking on stuff to look at when we go in. I’m not even joking, the experiment list keeps growing because the opportunity is unique and they don’t add significant amounts of time to the main experiment we’re doing.
(more…)The garden of forking paths
It’s called the butterfly effect and goes something like, “a butterfly can flap its wings and cause a hurricane on the other side of the world.” That’s not exactly true, like most things it’s an easy way to remember the concept. Something small can have a ripple effect that you may not be able to anticipate. In other words, chaos. The problem is chaos, the universe is not deterministic so predicting the future, even the immediate future, comes with a certain level of uncertainty. It’s only in hindsight can we trace back certain events and see the pattern and even then depending on the scale, it’s impossible to know which butterfly caused the hurricane or if the flapping of a butterfly’s wings prevented one.
(more…)Sometimes things get cancelled
Today was a big day. We got the equipment ready, the patient consented, and everyone on the clinical side of things was on the same page we were on. Things were going well. Surprisingly well in fact, that should’ve been the first sign something was going to go wrong. This time it wasn’t our fault though! Sometimes you just can’t catch a break, so maybe next time.
(more…)Off to the OR!
Tomorrow is the big day, our second experiment and while I’m a little nervous, I’m also excited to see what we can do. Last time around we had some issues… okay a lot of issues, but that’s because it was the first time we’ve ever tried something like this. This time around we worked with the team that will be in the OR with us so we know what they are doing and this time they know what we are doing. Basically we’re aiming for a whole lot less drama and a whole lot more useable data, meaning any usable data!
(more…)
Lunatic Laboratories 